Cell Adhesion Structural Integrity External Sensing Migration Requlation of Transport Communication adish Chapter 22 Kamm Chapter 2

麻省理工大学：《Systems Biology》Review lecture 2 Michaelis-Menten kinetics

L4: Cooperativity introduction 2 phage model n phage model (Hasty et al.) as example for applying mass action law

Fine tuned model for perfect adaptation spiro et a1.PNAs94,7263-7268(1997) A model of excitation and adaptation in bacterial chemotaxis

Organizational Remarks: ps#2,1b: Correction: Plot k, and for L= 0...2/K L (NOT: Plot ka and for L 0...2KL) Tomorrow's recitation topic: 'PS #2 support

creation of membrane associated minD first order first order autocatalytic inhibited by (linear, oligomerization) membrane minE, MM)

Review L15 Turing-Gierer-Meinhardt models Local excitation, global inhibition

Note final ps For question 2(a)the value of k'in the final equation(Eq 3b) needs to be rescaled Tuesday lecture will be for questions on the last problem set Juan)

Systems Biology x Network Biology GOAL: develop a quantitative understanding of the biological function of genetic and biochemical networks INPUT

THE INVESTMENT CASTING TEAM PROVIDING FOR“ REAL SOLUTIONS” THROUGH EXPERIENCE, UNDERSTANDING, QUALITY, FLEXIBILITY &s INOVATION NU-CAST, INC (NCD ALUMINUM INVESTMENT Londonderry, N.H. 603-432-1600 CASTINGS PROTO ENGINEERING ENGINEERING design