Part I Molecular Components of Cells 1 The Facts of Life: Chemistry Is the Logic of Biological Phenomena 2 Water: The Medium of Life 3 Thermodynamics of Biological Systems 4 Amino Acids and the Peptide Bond 5 Proteins: Their Primary Structure and Biological Functions 6 Proteins: Secondary, Tertiary, and Quaternary Structure 7 Carbohydrates and the Glycoconjugates of Cell Surfaces 8 Lipids 9 Membranes and Membrane Transport 10 Nucleotides and Nucleic Acids 11 Structure of Nucleic Acids 12 Recombinant DNA, Cloning, Chimeric Genes, and Synthetic Biology Part II Protein Dynamics 13 Enzymes—Kinetics and Specificity 14 Mechanisms of Enzyme Action 15 Enzyme Regulation 16 Molecular Motors Part III Metabolism and Its Regulation Part IV Information Transfer

Chapter 2 Water Chapter 3 Amino Acids, Peptides, and Proteins Chapter 4 The Three-Dimensional Structure of Proteins Chapter 5 Protein Function Chapter 6 Enzymes Chapter 8 Nucleotides and Nucleic Acids Chapter 9 DNA-Based Information Technologies Chapter 11 Biological Membranes and Transport Chapter 12 Biosignaling Chapter 13 Bioenergetics and Biochemical Reaction Types Chapter 14 Glycolysis, Gluconeogenesis, and the Pentose Chapter 16 The Citric Acid Cycle Chapter 17 Fatty Acid Catabolism Chapter 18 Amino Acid Oxidation and the Production of Urea Chapter 19 Oxidative Phosphorylation and Photophosphorylation Chapter 20 Carbohydrate Biosynthesis in Plants and Bacteria Chapter 22 Biosynthesis of Amino Acids, Nucleotides, and Related Molecules Chapter 24 Genes and Chromosomes Chapter 25 DNA Metabolism Chapter 26 RNA Metabolism Chapter 28 Regulation of Gene Expression

UNIT I: Protein Structure and Function Chapter 1: Amino Acids Chapter 2: Structure of Proteins Chapter 3: Globular Proteins Chapter 4: Fibrous Proteins Chapter 5: Enzymes UNIT II: Intermediary Metabolism Chapter 6: Bioenergetics and Oxidative Phosphorylation Chapter 7: Introduction to Carbohydrates Chapter 8: Glycolysis Chapter 9: Tricarboxylic Acid Cycle Chapter 10: Gluconeogenesis Chapter 11: Glycogen Metabolism Chapter 12: Metabolism of Monosaccharides and Disaccharides Chapter 13: Pentose Phosphate Pathway and NADPH Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins UNIT III: Lipid Metabolism Chapter 15: Metabolism of Dietary Lipids Chapter 16: Fatty Acid and Triacylglycerol Metabolism Chapter 17: Complex Lipid Metabolism Chapter 18: Cholesterol and Steroid Metabolism UNIT IV: Nitrogen Metabolism Chapter 19: Amino Acids: Disposal of Nitrogen Chapter 20: Amino Acid Degradation and Synthesis Chapter 21: Conversion of Amino Acids to Specialized Products Chapter 22: Nucle

一、基因治疗的策略 The Strategy of Gene Therapy 二、基因转移技术 The Technique of Gene Transfer 三、基因干预 Gene Interference 四、治疗基因的受控表达 Regulated Expression of Therapeutic Gene 五、基因治疗的应用研究 The Application of Gene Therapy

本课以高等数学、生物学、生物化学、生物统计学为基础，在学完普通遗传学及数量遗传学的基础上而开设的一门专业基础课。 要求学生熟练掌握动物育种学的常用术语，了解动物生长发育规律，掌握选种选配的进本理论和方法以及改良动物个体与群体遗传结构的措施，要求学生根据育种的基本原理与育种工作实 质相结合，正确设计育种计划，把育种的基本原理灵活的运用到生产实践中去

第一节 血浆蛋白质及其异常 第二节 氨基酸代谢紊乱 第三节 核苷酸代谢紊乱 第四节 检测方法评价

(一)、课程的性质地位和任务: 动物遗传学是农业院校中动物科学本科专业的专业基础课。动物遗 传与生物化学、细胞生物学、动物学、育种学、繁殖学、生物进化等学科 关系密切。是本专业学生的必修课程,也是学好育种和繁殖学的前期科 学,而且对于学生的在生物技术等相关领域的进一步深入学习不可缺少的 理论基础知识。同时也为科研和实践能力的提高和加强提供实验手段,锻 炼学生的思维和创新能力

第一节 DNA损伤 DNA Damage 第二节 DNA损伤的修复 The repair of DNA damage 第三节 DNA损伤和修复的意义 The significance of DNA damage and repair

第一节 原核生物转录的模板和酶 第二节 原核生物的转录过程 The process of transcription 第三节 真核生物RNA的生物合成 The Biosynthesis of Eukaryote RNA 第四节 真核生物RNA的加工和降解

第一节 复制的基本规律 Basic Rules of DNA Replication 第二节 DNA复制的酶学和拓扑学变化 The Enzymology of DNA Replication 第三节 原核生物DNA复制过程 复制的起始 DNA链的延长 复制的终止 原核生物DNA复制过程 第四节 真核生物的DNA生物合成 第五节 逆转录和其它复制方式 Reverse Transcription and Other DNA Replication Ways