that peptides derived from the antigen be displayed within the cleft of an MHC peptide-Mhcthe m ormation of the Antigen Processing for Presentation by Class I MHC Molecules Self-MHC Restriction of T Cells Class tides that Role of Antigen-Presenting Cells Evidence for Two Processing and Presentation Pathways

lecular association similar to an enzyme-substrate interaction, with an important distinction: it does not lead to an irreversible chemical alteration in either the antibody or the antigen. The association between an anti Fluorescent Antibody Staining Reveals Intracellular body and an antigen involves various noncovalent interac- tions between the antigenic determinant, or epitope, of the ntigen and the variable-region(vH/Vi) domain of the an- a Strength of Antigen-Antibody Interactions tibody molecule, particularly the hypervariable regions

present on the B-cell membrane and secreted by plasma cells. Membrane-bound antibody con- fers antigenic specificity on B cells; antigen-specific prolifer- ation of B-cell clones is elicted by the interaction of membrane antibody with antigen Secreted antibodies ci culate in the blood, where they serve as the effectors of hu- moral immunity by searching out and neutralizing antigens or marking them for elimination. All antibodies share struc

body. These organs can be classified functionally nto two main groups. The primary lymphoid organs provide appropriate microenvironments for the development and maturation of lymphocytes. The secondary lymphoid organs rap antigen from defined tissues or vascular spaces and are sites where mature lymphocytes can interact effectively with that antigen. Blood vessels and lymphatic systems connect these organs, uniting them into a functional whole Carried within the blood and lymph and populating the Macrophage Interacting with

通过本课程的讲授与学习，使学生掌握医学微生物学基本理论、基本 知识和基本技术，为学习其他基础医学和临床医学的相关学科打下基础。 本课程的内容分理论教学和实验教学两部分。医学微生物学理论教学内容又可分细菌总论、细菌各论、其 他微生物和病毒四个篇幅。分别阐述了多种微生物的生物学特性、致病性、免疫性以及所致病的诊断和防 治

第一节病毒感染对寄主组织器官的损伤 第二节病毒的持续性感染 第二节病毒感染对免疫系统的损伤

第一节概念 第二节凝聚性反应 第三节标记抗体技术 第四节补体参与的试验 第五节中和试验

第一节免疫的基本概念 第二节抗原 第三节抗体 第四节抗体产生的克隆选择学说

病因 一、遗传基因缺陷 二、环境因素 三、母体因素 四、胎盘内分泌功能不足 五、免疫因素

组织与胚胎学课件：免疫系统