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13.1 癌细胞的基本知识 13.2 肿瘤发展的阶段 13.3 肿瘤发生遗传学 13.4 肿瘤的表观遗传学改变 13.5 癌细胞中基因表达谱的异常改变 13.6 肿瘤诊断与检测 13.7 肿瘤治疗
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Section 1 Introduction of lipid Classfication and structure Distribution and function Digestion and absorption Section 2 Fat metabolism 1. Fat mobilization and hydrolysis 2. Fatty acid β-oxidation 3. Ketone body formation 4. Fat synthesis Fatty acid and glycerol synthesis Section 3 Metabolism of Phospholipid Phospholipids (PL) cholesterol and cholesteryl ester glycolipids lipoid Section 4 Cholesterol metabolism Section 5 the metabolism of plasma lipoprotein
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1. Large four protein complexes Ⅰ,Ⅱ,Ⅲ and Ⅳ embedded in the inner mitochondrial membrane. 2. Electron transport via the respiratory chain. 3. ATP synthesis by oxidative phosphorylation. 4. common poisons that block electron transport and oxidative phosphorylation. 5. Substrates shuttle into mitochondial respiratory chain
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发育生物学(Development Biology)是在胚胎学基础上,结合了细胞生物学、遗传学、生物化学和分子生物学等诸多现代生物学分支学科及各种现代生物学技术手段,研究生物发育本质的科学。 一. 学习医学发育生物学的意义 二. 医学发育生物学的研究/学习内容(相关概念、特征、基本规律和科学问题) 三. 教学安排
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The nucleus is the biggest and most important organelle of the cell. The presence of the nucleus is the principal feature that distinguishes eukaryotic from prokaryotic cells Almost eukaryotic cells have the nucleus except mature red blood cells of mammals and sieve cells of high plants etc.. By housing the cell's genome, the nucleus serves both as the repository of genetic information and as the control
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7.4.1 Two types of proteins: 7.4.2 Protens synthesized can move or transport between compartments in different ways 7.4.3 Soluble proteins destined for secretion or residence within the lysosomal and other EMS vacuolate lumens 7.4.4. Proteins destined for incorporation into the membranes of ER and other EMS or plasma membranes
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Countless divisions of a single-celled zygote produce an organism of astonishing cellular complexity and organiza- tion. Any individual cell is bound to die, because cells are subject to wear and tear as well as to accidents. 25 million cells are undergoing division each second in an adult human and blood cells renewed at the rate of about 100 million per minute. If an organism is to continue to live
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The generation of metabolic energy is a major activity of all cells, and two cytoplasmic organelles are specifically devoted to energy metabolism and the production of ATP. Mitochondria are responsible for generating most of the useful energy from the breakdown of lipids and carbohydrates, and chloroplasts
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一、酶的概念及特性 酶(enzyme)是活细胞内产生的具有高度专一性和催化效率的蛋白质, 又称为生物催化剂,生物体在新陈代谢过程中,几乎所有的化学反应都是 在酶的催化下进行的。 酶是生物催化剂(biological catalyst),具有两方面的特性,既有与一般 催化剂相同的催化性质,又具有一般催化剂所没有的生物大分子的特征。 酶与一般催化剂一样,只能催化热力学允许的化学反应,缩短达到化 学平衡的时间,而不改变平衡点
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11. 4. The nucleolus The most prominent substructure within the nucleus during interphase is the nucleolus. 100 years ago, one found a big spherical structure, called nucleolus within the nucleus, but up until 1960s, it was not identified that the nucleolus is a ribosome production factory designed to fulfill the need for large scale transcription and processing
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