X-Ray diffraction is an important and powerful tool for determining the solid state structure of compounds. Modern advances have made data collection and structure solution almost routine for many small molecules To use this technique, however, good quality single crystals are still needed. In this exercise you will experiment with the art of growing single crystals

equipment and supavision by appropriate individuak You bear the sol responsibility, liability, and risk for the implemcntation of such safety procedures a ares. MIT shall have no responsibility, liability, risk for the content or implementation of of the mat

Chemists use spectroscopy (Ir, UV-Vis, NMR) to determine molecular structure. spectroscopy: technique that measures the amount of radiation a substance absorbs at various wavelengths(based on the quantization of molecular energy levels Molecules exist in quantized energy states (rotational, vibrational, and electronic quantum states) Molecules absorb discrete amounts of energy(ae)and are excited to higher

described in these materials are potentially hazardous and require a high lcvel ofsafity training special facilitics and equipment, and supavision by approprinte duals. You bear the sol responsiblity, liability, and risk for the impkemcntation of such safety procedures and measures. MiT shall have no responsibility, liability, ar risk for the content ar implem of ay of the matcrial presented. Legal Notices

This is two-day- experiment. Do not start this experiment unless you have two free lab days to complete it.*** Techniques Checklist: Picking the correct eluent Adsorbtion of a crude mixture onto silica gel Separating complex mixtures using gradient elution Pre-lab Discussion: Suggest limited list of eluent solvent systems Discuss sample adsorption and gradient elution strategies

described in these matorials arc potentinlly hazandous and require a high levd ofsafety training spccial facilitics and equip mant, and supervision by approp iate individuals. You bea the sole responsibility, lisbility, and risk for the implamnentation of such safcty procedures and mcasures. MIT shall have no respongibility, liability, or risk for the content or implementationc any of the material presanted. Legal Notices

WARNING NOTICE: The erperimants descnbed in these materials are potentially hao ardous and require a high level ofsafcty training special facilitics and equipment, and supervision by approprinte individuals. You bear the solc responsibility, liability, and risak for the implemcntation of such safdty procedunes and measures. MrT shall have no responsiblity, liability, risk for the content or implemcutation of amy of the matcrial presented. Legal Notices

《有机化学实验》课程教学资源（讲义）实验二十五——二十七 创新、设计性实验

《有机化学实验》课程教学资源（讲义）实验四 液体有机化合物的分离——分馏

《有机化学实验》课程教学资源（讲义）实验五 固体有机化合物的提纯——重结晶