Development of Classification of Acute Leukemia 1976 French-American-British(FAB) Cooperative Group proposed classification of acute leukemia based on morphologic criteria that were subsequently refined in 1981 and 1985 1986 Morphologic, immunologic and cytogenetic
Properties of herpesviruses Enveloped double stranded DNA viruses. Genome consisits of long and short fragments which may be orientated in either direction, giving a total of 4 isomers
Live difficult diagnosis clinical picture, skin biopsy, corneal impression(antibodies only appear very late) Dead- brain sent to Onderstepoort Negri bodies in cytoplasm of brain cells; immunofluorescence virus isolation
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