Epidemiology 6th leading cause of death in U.S. Number one Among the infectious diseases 6 million patients annually in US Incidence 5~10/1,000/year Mortality in OPD patients 1-5 % but Inpatients 25%, ICU 50-60%
General Consideration Antenatal cardiovascular changes Blood volume increase by 40%-60%0 Peaking at 32-34 weeks the expansion in plasma volume is greater than that expansion of red cell mass Cardiac output Increase by 40%6-50% Peaking at 20-24 weeks