Chapter 2 Water Chapter 3 Amino Acids, Peptides, and Proteins Chapter 4 The Three-Dimensional Structure of Proteins Chapter 5 Protein Function Chapter 6 Enzymes Chapter 8 Nucleotides and Nucleic Acids Chapter 9 DNA-Based Information Technologies Chapter 11 Biological Membranes and Transport Chapter 12 Biosignaling Chapter 13 Bioenergetics and Biochemical Reaction Types Chapter 14 Glycolysis, Gluconeogenesis, and the Pentose Chapter 16 The Citric Acid Cycle Chapter 17 Fatty Acid Catabolism Chapter 18 Amino Acid Oxidation and the Production of Urea Chapter 19 Oxidative Phosphorylation and Photophosphorylation Chapter 20 Carbohydrate Biosynthesis in Plants and Bacteria Chapter 22 Biosynthesis of Amino Acids, Nucleotides, and Related Molecules Chapter 24 Genes and Chromosomes Chapter 25 DNA Metabolism Chapter 26 RNA Metabolism Chapter 28 Regulation of Gene Expression

UNIT I: Protein Structure and Function Chapter 1: Amino Acids Chapter 2: Structure of Proteins Chapter 3: Globular Proteins Chapter 4: Fibrous Proteins Chapter 5: Enzymes UNIT II: Intermediary Metabolism Chapter 6: Bioenergetics and Oxidative Phosphorylation Chapter 7: Introduction to Carbohydrates Chapter 8: Glycolysis Chapter 9: Tricarboxylic Acid Cycle Chapter 10: Gluconeogenesis Chapter 11: Glycogen Metabolism Chapter 12: Metabolism of Monosaccharides and Disaccharides Chapter 13: Pentose Phosphate Pathway and NADPH Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins UNIT III: Lipid Metabolism Chapter 15: Metabolism of Dietary Lipids Chapter 16: Fatty Acid and Triacylglycerol Metabolism Chapter 17: Complex Lipid Metabolism Chapter 18: Cholesterol and Steroid Metabolism UNIT IV: Nitrogen Metabolism Chapter 19: Amino Acids: Disposal of Nitrogen Chapter 20: Amino Acid Degradation and Synthesis Chapter 21: Conversion of Amino Acids to Specialized Products Chapter 22: Nucle

第一节 蛋白质的分子组成 第二节 蛋白质的分子结构 第三节 蛋白质结构与功能的关系 第四节 蛋白质的理化性质及其分离纯化

第一节 概述 第二节 糖的无氧分解 第三节 糖的有氧氧化 第四节 磷酸戊糖途径 第五节 糖原的合成与分解 第六节 糖异生 第七节 血糖及其调节

第一节 蛋白质的营养作用 第二节 蛋白质的消化、吸收与腐败 第三节 氨基酸的一般代谢 第四节 氨的代谢 第五节 个别氨基酸的代谢

第一节 不饱和脂肪酸的分类及命名 第二节 脂类的消化与吸收 第三节 甘油三酯的代谢 第四节 磷脂的代谢 第五节 胆固醇代谢 第六节 血浆脂蛋白代谢

第一节 核酸的化学组成 第二节 核酸的一级结构 第三节 DNA的空间结构与功能 第四节 RNA的空间结构与功能 第五节 核酸的理化性质及其应用

Part I Molecular Components of Cells 1 The Facts of Life: Chemistry Is the Logic of Biological Phenomena 2 Water: The Medium of Life 3 Thermodynamics of Biological Systems 4 Amino Acids and the Peptide Bond 5 Proteins: Their Primary Structure and Biological Functions 6 Proteins: Secondary, Tertiary, and Quaternary Structure 7 Carbohydrates and the Glycoconjugates of Cell Surfaces 8 Lipids 9 Membranes and Membrane Transport 10 Nucleotides and Nucleic Acids 11 Structure of Nucleic Acids 12 Recombinant DNA, Cloning, Chimeric Genes, and Synthetic Biology Part II Protein Dynamics 13 Enzymes—Kinetics and Specificity 14 Mechanisms of Enzyme Action 15 Enzyme Regulation 16 Molecular Motors Part III Metabolism and Its Regulation Part IV Information Transfer

一、基因治疗的策略 The Strategy of Gene Therapy 二、基因转移技术 The Technique of Gene Transfer 三、基因干预 Gene Interference 四、治疗基因的受控表达 Regulated Expression of Therapeutic Gene 五、基因治疗的应用研究 The Application of Gene Therapy

酶：是一类由活细胞合成的，对其特异底物起高效催化作用的蛋白质。 第一节 酶的分子结构与功能 第二节 酶的工作原理 第三节 酶促反应动力学 第四节 酶的调节 第五节 酶的分类及命名 第六节 酶与医学的关系