1. Solubility 2. Some Solvents for Liquid Preparations 3. Preparation of Solutions 4. Oral Solutions and Preparations for Oral Solution 5. Syrups 6. Elixirs 7. Tinctures 8. Proper Administration and Use of Liquid Peroral Dosage Forms 9. Topical Solutions and Tinctures 10. Vaginal and Rectal Solutions 11. Topical Tinctures 12. Topical Oral (Dental) Solutions 13. Miscellaneous Solutions 14. Nonaqueous Solutions 15. Extraction Methods for Preparing Solutions

§.3 注射剂的制备 §4 注射剂的附加剂 §.5 注射剂的制备 §.6 中药注射剂的质量检查 §.7 输液的制备 §.8 Sterile Injection Powder §.9 Eye-drop

Section one: Site-specific drug delivery Chapter one Site-specific drug delivery using liposomes as carriers.3 Chapter two Site-specific drug delivery utilizing monoclonal antibodies .35 Section two: Polymers, implantable drug delivery Chapter three Role of polymers in drug delivery .63 Chapter four Implants in drug delivery. 115 Section three: Oral drug delivery Chapter five Oral drug delivery .149 Section four: Transdermal, intranasal, ocular, and miscellaneous drug delivery Chapter six Transdermal drug delivery .207 Chapter seven Intranasal and ocular drug delivery .249 Chapter eight Miscellaneous forms of drug delivery .289

I. Ointments II. Compendial requirements for ointments III. Creams IV. Gels V. Miscellaneous semisolid preparations: pastes and plasters VI. Features and use of dermatologic preparations VII. Features and use of ophthalmic ointments and gels VIII. Features and use of nasal ointments and gels IX. Features and use of rectal preparations X. Features and use of vaginal preparations

I. The rationale for extended-release pharmaceuticals II. Terminology III. Extended-release oral dosage forms IV. Delayed-release oral dosage forms V. USP requirements and FDA Guidance for modified-release dosage forms VI. Clinical considerations in the use of oral modified-release dosage form VII. Packaging and storing modified-release tablets and capsules

介绍制剂生产中的灭菌方法 无菌操作法 衡量灭菌可靠性的参数 洁净室的设计与空气净化技术 无菌检查法

胶囊剂（Capsules）系指原料药物与适宜辅料充填于空心胶囊或密封于软质囊材中制成的固体制剂。丸剂（pills）系指原料药物与适宜的辅料制成的球形或类球形固体制剂

I. Ointments II. Compendial requirements for ointments III. Creams IV. Gels V. Miscellaneous semisolid preparations: pastes and plasters VI. Features and use of dermatologic preparations VII. Features and use of ophthalmic ointments and gels VIII. Features and use of nasal ointments and gels IX. Features and use of rectal preparations X. Features and use of vaginal preparations

第一节 概述 第二节 药物稳定性的化学动力学基础 第三章 制剂中药物的化学降解途径 第四节 影响药物制剂降解的因素及稳定化方法 第五章 固体药物制剂稳定性的特点及降解动力学 第六节 药物稳定性试验方法 第七节 新药开发过程中药物系统稳定性研究

本章要求： 1、掌握 制剂稳定性意义、研究范围、化学动力学概述 2、熟悉 制剂中药物化学降解途径 3、掌握 影响制剂降解因素及稳定化方法 4、掌握 药物稳定性试验方法 5、熟悉 经典恒温法 第一节 概述 第二节 药物稳定性的化学动力学基础 第三节 药物制剂的化学降解途径 第四节 影响药物制剂降解的因素 第五节 固体药物制剂的稳定性 第六节 药物制剂稳定性的试验方法