一、显性表现的多样性 分四种: 完全显性、不完全显性、共显性、超显性 1.完全显性: Mendel所研究的豌豆的7对相对性状,F1所表现的性状都和亲本之一完全一样,既不是中间型,也不是双亲的性状同时出现,这样的显性表现称为完全显性( complete dominance)

Bacterial Genetics Key Requirements Understand how genetic mapping is achieved in bacteria: Co-transformation, F factor Hfr strain co-transduction and some understanding of phage genetics 2. Read the textbook and do the problem set at the back

Eukaryotic Chromosomes are composed of DNA, Histone and Nonhistone Proteins Histones: H1 H2A. H2 B, H3, H4. The later 4 form nucleosomes(100 A)and thus called core histones. H1 plays a role in forming 300 A superhelix Histones are rich in basic amino acids Nonhistone proteins play a variety of functions

Medical Genetics Genes are entities that parents pass to offspring during reproduction

Medical Genetics Gene Mutation Change in genes caused by change in structure of the dna

The most common gene change involves a single base mismatch--a misspelling--placing the wrong base in the DNA. At other times, a single base may be dropped or added. And sometimes large pieces of DNA are mistakenly repeated or deleted

single-gene disorder or monogenic disorder Some disorders result when a mutation causes the product of a single gene to be altered or missing. These disorders are inherited in simple patterns similar to or identical with those described by Mendel for certain discrete characteristics in garden peas. Therefore it's also called mendelian diseases

前面所介绍的遗传性状都是由细胞核内染色体 上的基因即核基因所决定的,由核基因所决定的遗 传现象和遗传规律称为细胞核遗传或核遗传。 生物的某些遗传现象并不是或者不完全是由核基因 所决定的,而是取决于或部分取决于细胞质内的基因

1.孟德尔分离规律、验证、应用; 2.显性性状的表现及与环境的关系; 3.二对相对性状的遗传; 4.多对相对性状的遗传; 5.基因互作; 6.基因的作用和性状的表现; 一因多效、多因一效

孟德尔遗传以及连锁遗传中论述的可遗传变异均是由于 基因重组的结果,不是基因本身发生了质的变化。 如:黄子叶、园粒×绿子叶、皱粒 黄、园,黄、皱,绿、园,绿、皱 本章讨论染色体上基因发生改变