recognition by most T cells from recognition by B iction. In most cases, both th maturati vation of ma the involver diversity o CD4\ and CD class I MHC Activat Engagement of TcR by Peptide: MHC Initiates interaction of th n antigenic Signal Transduction tide displayed though the sp
cell receptor when complexed with MHC,are called antigens. The molecular properties of antigens and he way in which these properties ultimately contribute to immune activation are central to our understanding of the mmune system. This chapter describes some of the molecu- Complementarity of Interacting Surfaces of Antibody(left) lar features of antigens recognized by B or T cells. The chap and Antigen(rig ter also explores the contribution made to immunogenicity by the biological system of the host; ultimately the biological system determines whether a molecule that combines with a a Immunogenicity Versus Antigenicity Bor T cells antigen-binding receptor can then induce an im
