1. Two hydrogels are prepared from two different candidate polymers for controlled release of a protein drug, interleukin-2(IL-2). The gels exhibit the same swelling ratio at equilibrium, but gel A(formed by cross-linked polymer A, repeat unit molecular weight Mo= 100 g/mole)has

A recent study of controlled release of a model small-molecule drug from poly(lactide-co-glycolide) microspheres prepared by the single-emulsion method found that the diffusion constant of the drug through the polymer was best related to the polymers molecular weight according

5 points/problem(20 points total) 1. Two hydrogels are prepared from two different candidate polymers for controlled release of a protein drug, interleukin-2(IL-2). The gels exhibit the same swelling ratio at equilibrium, but jel a (formed by cross-linked polymer A, repeat unit molecular weight Mo= 100 g/mole)has a molecular weight between cross-links of 3,000 g/mole, while gel B (formed from cross linked polymer B, Mo=95 g/mole) has a molecular weight between crosslinks of

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