Composition of eggs %o Water Protein Fat CHO Whole10074.612.111212 White5888.010.10.20.8 Yok314801643292.0

Molecular switches in the cell: fibronectin as a mechanical switch (vogel, 2002) Fibronectin is an adhesion protein secreted by cells and assembled into fibrils to support adhesion and migration Composed of\ of fibronectin repeats Fnl, Fnll, and Fnlll connected by short linkers of varying flexibility One particular Fnlll repeat, Fnlll10

1. (4 pts) An early study in the development of peptide-presenting biomaterials showed that polymer surfaces bearing RGD peptides at a density equivalent to -10 peptides per each cell was sufficient to promote cell attachment, spreading and subsequent cell growth. In contrast, when whole fibronectin protein was adsorbed to polymer surfaces, it was found that many more copies of the

1. Two hydrogels are prepared from two different candidate polymers for controlled release of a protein drug, interleukin-2(IL-2). The gels exhibit the same swelling ratio at equilibrium, but gel A(formed by cross-linked polymer A, repeat unit molecular weight Mo= 100 g/mole)has

ANTITHROMBOTIC PROPERTIES Inhibition of platelet aggregation: PGL NO, ADPase Anticoagulant -binding and inhibition of thrombin: Antithrombin acceleration by heparin-like molecules, thrombomodulin activation of protein C/S, a2-macroglobulin. Fibrinlysis: Tissue plasminogen activator (tPA)

Definition PEM is manifested primarily by inadequate dietary intakes of protein and energy. PEM is almost always accompanied by deficiencies of other nutrient. PEM can be divided as primary PEM and secondary PEM

朊毒体(prion)/传染性蛋白粒子/朊粒/朊病毒: 是一种不同于细菌、病毒或类病毒的在分类上 尚示定论的病原因子。其本质为由正常宿主细胞基 因编码的、构象异常的蛋白质,称为朊蛋白(prion protein,PrP),目前尚未检出任何核酸成分,是 人和动物的传染性海绵状脑病(transmissible spongiform encephalopathies,tses)的病原体

一、掌握蛋白质的元素组成及特点、组成人体蛋白质的基本单位--氨基酸的种类及通式。 二、掌握蛋白质一、二、三、四级结构的概念及其稳定因素、掌握蛋白质二级结构的基本形式,了解肽、肽键、肽单元、模序、结构域的概念 三、掌握蛋白质(氨基酸)的等电点和两性电离、蛋白质变性及沉淀、盐析的概念

Assay:化验,分析,测定。 Enzyme activity: unit() is defined as the amount of enzyme which convert 1 micromole (umol) of substrate to product(s) in 1 minute under specified conditions. Specific activity: enzyme activity expressed per unit mass of protein present. (units/mg)

Reversible ligation of Ubiquitin and Ubls to other proteins. Figure by MIT OCW. After Figure 1 in Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000 Aug: