Markov Hidden markov models for dna Markov Models for splice sites Hidden Markov models looking under the hood The Viterbi algorithm Real World HMMs

Review of markov HMM Models for dna Markov Models for splice sites Hidden Markov models looking under the hood The Viterbi algorithm Real World HMMs

Review of protein structure hierarchy Nonpolar, Hydrophobic R-grou Primary structure Glycin (Gly, G) Aa,A≌ alina (VaL V. Leucine(Lou, L) Isoleucine{,非 MAAAAAAGPEMVRGQVE 20 amino acids Phenylalanine(Ph,月

For a molecular simulation or model you need 1. a representation of the protein 2. An energy function 3. a search algorithm or optimizer

1. Overview-the many levels of systems biology 2. Experimental methods for measuring protein-protein interactions and their limitations 3. Data sources for information about proteins and their

Ab initio =from the beginning in strictest sense uses first principles, not information about other protein structures In practice, all methods rely on empirical observations

MAIN THEORIES ON PSYCHOLOGICAL DEVELOPMENT Learning Theory -Watson, Bandura Psychoanalytic Theory -Freud, Erikson Cognitive Development- Piaget

Chapter 5 Neonate and Neonatal diseases 1. Neonatal outline 2. Neonatal respiratory diseases 3. Neonatal jaundice and hemolysis 4 Neonatal brain diseases 5, Neonatal infection

bilirubin metabolism RBC Bilirubin(胆红素) Free bilirubin(游离胆红素)

Determination of the relative movement of the two walls from the tension joints