General introduction Ion channels G-protein coupled receptors Second messengers Tyrosine kinase receptors From plasma membrane to the nucleus: Regulation of gene expression Cytokine signaling Cell cycle Apoptosis
Much of the catalytic power of enzymes comes from their bringing sub- strates together in favorable orientations in enzyme-substrate (ES)com- plexes. The substrates are bound to a specific region of the enzyme called the active site. Most enzymes are highly selective in their binding