长期以来,各种传统的特殊染色技术、免疫组 织化学、原位杂交等研究方法均建立在常规病理组 织切片基础上,一张玻片上只能载有限的组织做 种测试,仅用于日常临床病理诊断尚可胜任,但要 从事大规模、多样本的科研则费时、费力。自1998 年由 Kononen等叫构建了第一个组织微阵列后,组 织芯片技术得到极大发展,其无疑给病理学研究开 辟了新天地。目前已有大量应用这一技术进行肿瘤 病理学研究的报道,短短数年国内关于运用组 图1b单个组织芯(乳腺浸润性导管癌)HE染色。 织芯片的文章已达126篇之多(截止2004年12 月)9其主要集中于免疫组织化学和原位杂交技 术在组织芯片上对各种不同肿瘤的研究,并充分体 现了该技术高通量( high-throughput)、快速、省时 用途广等优点,同时运用该技术也发现了一些肿瘤 特异性基因产物和与肿瘤生物学行为有关的免疫 标志物。当然在运用该技术时也发现了一些问题

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一、选择题答案 1.B2.A3.B4.A5.1C5.2 6.C7.d8.C9.10

physicsweb Physics news, jobs and resources Fermionic first for condensates Physics in Action: March 2004 The creation of the first fermionic condensate will herald a new generation of research into the properties of superfluids and superconductors

SPIRIT UPDATE: Spirit probes deeper into 'Clovis'outcrop-sol 209-218, August 23,2004 Spirit continued work over the past nine sols at a rock called \Clovis.\ The rover used roscop its rock abrasion tool, microscopic imager, alpha particle X-ray- spectrometer,and Mossbauer spectrometer to probe deeper into the history of this rock. Clovis is the most altered rock encountered by Spirit to date. It is part of a rock outcrop located on the\West Spur\ of the \Columbia

Evicting einstein ScienceaNASa a physics experiment on the drawing board for the International Space Station could help find the grand unifying\Theory of Everything March 26, 2004: Sooner or later, the reign of Einstein, like the reign of Newton before him, will

一、选择题(30分,答案请写在答卷纸上) 1.在1mol的盐酸溶液中,已知Ecece1.28v,0.1000moll的e有99.9%被还原成Ce3时,该电对的电极电位为: (A)1.22V(B)1.10V(C)0.90V(D)1.28V

IG Aln Happy New Year 2004 UHF ndio REM telecom HW \ Front SSPA Mars Rovers mEr-a \ Spirit landed Sat 1/3 11 35pm ET Body structure (Warm Electronics BoxWeb).Refhttp://marsrovers.jplnasagov (imAgeistakenfromNasa'SWebsitehttp://www.nasa.gov.) We won' t be designing a mars rover this iap, but You will learn about the design process and fundamenta

2004年度七年制见习PBL及临床思维教学

1.1 Dreamweaver MX2004的工作环境 1.2创建新站点