What is rA? Y RA is a chronic polyarticular inf lammatory arthritis that involves not only small joints of the hands and feet but also systemic organs Y Pathologic change: chronic synovitis with pannus (IfL
Epidemiology 6th leading cause of death in U.S. Number one Among the infectious diseases 6 million patients annually in US Incidence 5~10/1,000/year Mortality in OPD patients 1-5 % but Inpatients 25%, ICU 50-60%
Classification of diabetes(ADA -1997) Type 1 .(beta-cell destruction, usually leading to absolute insulin deficiency) Autoimmune Idiopathic Type2 (may range from predominantly insulin resistance with relative insulin deficiency to a predominantly secretory defect with or without insulin resistance)