美国国家生物技术信息中心( National Center for biotechnology Information fa] 称NCBI)创建于1988年。 1991年,NCB|开发了 Entrez数据库查询系 统,用于对 Gen Bank等分子生物学和生物 医学文献摘要( Medline)等数据库的査询 ( Schuler et al,1996)
生物信息学现状和重要研究方向 1.1什么是生物信息学? Genome informatics is a scientific discipline that encompasses all aspects of genome information acquisition, processing, storage, distribution, analysis, and interpretation. 它是一个学科领域,包含着基因组信息的获取、处 理、存储、分配、分析和解释的所有方面
3-1 Introduction 3-2 Definition Architecture 3-3 Why have Architecture 3-10 3-5 Definition Architecture 3-6 The V.and X.standards 3-7 Advs and disadvs of standards 3-8 Communication Architecture 3-9 ISO Reference Model 3-4 Standards making org 3-11 Internet Architecture 3-12 Manufactures Architecture 3-13 A caveat about 3-14 Layered architecture