《遗传学与社会》课程教学资源：性别决定的分子机制

《遗传学与社会》课程教学资源：性别决定基因的研究进展（南京铁道医学院）

How DNA as genetic materials was established (also summarized in er including structure and components Basic properties of DNA, i xt slide)

Restriction enzymes are used for cutting DNA at precise locations Vectors are used for the propagation of cloned DNA fragments Libraries of cloned DNA fragments allow searching for a specific DNA fragment

Cells reproduce via a cell cycle Meiosis is the key to sexual reproduction and Mendel’s rules Sex determination, sex linkage and chromosome nondisjunction supported the chromosome theory

Extensions of Mendelian Analysis Interactions between alleles of one gene. Multiple alleles, incomplete dominance, codominance Interactions between alleles of two genes. New phenotypes, epistasis Relationship between genotype & phenotype lethals, variable penetrance, conditional alleles

Genetics is a different biology class Reading, attending lectures Andunderstanding the concept-notmemorizing Do problem sets

一、 概念（16 分，每个 2 分） 1、 同源染色体 2、 复等位基因 3、显性上位作用 4、 基因定位 5、 转导

一、 概念（每题 2 分，共 16 分） 1、多倍体 2、重组子 3、开放阅读框架 4、插入序列 5、Alu 家族 6、基因扩增 7、异源 DNA 8、假显性现象

一、 概念（16 分） 1、正向突变 2、同源多倍体 3、转化 4、DNA 变性 5、重迭基因 6、突变子 7、基因簇 8、质粒