Properties of herpesviruses Enveloped double stranded DNA viruses. Genome consisits of long and short fragments which may be orientated in either direction, giving a total of 4 isomers

Hemorrhogic Fever Virus Hantaar Virus or HEMORRHAGIC FEVER with renal syndrome virus HFRS Xing Jiang Hemorrhogic Fever Virus Dept. of microbiology and parasitology

Similar to Viruses Atypical Agents Small Filterable Need host cells No machinery for energy generation of protein synthesis

Live difficult diagnosis clinical picture, skin biopsy, corneal impression(antibodies only appear very late) Dead- brain sent to Onderstepoort Negri bodies in cytoplasm of brain cells; immunofluorescence virus isolation

Viral gastroenteritis It is thought that viruses are responsible for up to 3/4 of all infective diarrhoeas Viral gastroenteritis is the second most common viral illness after upper respiratory tract infection

Genera of picornaviruses Enterovirus Polio Diseases of the human (and other alimentary tract Coxsackie a and B (e.g. polio virus

Category of sample Blood, Urine, Stool, nasal washing, nasal swab, throat swab, saliva, sputum, rectal swab, vesicle fluid scraping or swab) tissue, brain biopsy, cerebrospinal fluid, et

What does a pathogen have to do? Infect (infest) a host Reproduce(replicate) itself Ensure that its progeny are transmitted to another host

Medical Virology Dept. of Medical Microbiology and Parasitology Shanghai Second Medical University Shanghai, China. E.mail:(xkguoshsmu.edu.cn)

Biological Features Structure and chemical composition Developmental cycle Staining properties Antigens Growth and metabolism Characteristics of host-parasite- relationship Classification