Review of markov HMM Models for dna Markov Models for splice sites Hidden Markov models looking under the hood The Viterbi algorithm Real World HMMs

CATER 8 The replication of wa Teaching Arrangement Watch animation-Understand replication

Properties of herpesviruses Enveloped double stranded DNA viruses. Genome consisits of long and short fragments which may be orientated in either direction, giving a total of 4 isomers

Why the hype? Microarray platforms CDNA VS oligo technologies Sample applications Analysis of microarray data clustering of co-expressed genes some classic microarray papers

Markov Hidden markov models for dna Markov Models for splice sites Hidden Markov models looking under the hood The Viterbi algorithm Real World HMMs

Outline FASTA, Blast searching, Smith-Waterman Psi-Blast Review of Genomic DNA structure Substitution patterns and mutation rates Synonymous and non-Synonymous substitutions Jukes-Cantor Model Kimura's Two-Parameter Model

Medical Genetics Gene Mutation Change in genes caused by change in structure of the dna

一、前言 二、诱发基因突变的因素 三、基因突变的一般特性 四、基因突变的分子机制 五、DNA损伤的修复

本章重点讨论RNA的生物合成,对RNA的合成后加工和RNA的复制作一般介绍。 第一节DNA指导下RNA的合成(转录) 第二节RNA转录后加工 第三节RNA指导下RNA的合成(RNA的复制) 第四节核酸生物合成的抑制剂

一、 孟德尔学说奠定了遗传学基础 二、 基因是一段DNA序列 三、 基因工程的操作和应用