epidemiology Labor and delivery between28-36+6 weeks 5%-10% be the leading cause of perinatal morbidity and mortality Survival rates have increased and morbidity has decreased because of technologic advances

妊娠滋养细胞疾病:来源于胎盘绒毛滋养细胞 的疾病,包括葡萄胎、侵蚀性葡萄胎、绒癌和 一类少见的胎盘部位滋养细胞肿瘤

Normal Pregnancy Pregnand The course that the embryo and the fetus grow in the maternal body Stages f pregnancy Early pregnancy: $12 weeks Mid pregnancy:≥13 weeks,≤27 weeks Late pregnancy: 228 weeks Term pregnancy:≥37 weeks,<42 weeks

定义 孕28周后,胎盘附于子宫下段,甚至胎盘下缘 达到或覆盖宫颈内口,位置低于胎儿先露部 ,称为前置胎盘

病因 一、影响因素 早婚早育、过早性生活、密产多产、 经济状况、种族、地理环境等 高危男子一阴茎癌、前列腺癌、前妻曾患宫颈 癌 二、人乳头瘤病毒(HPV)(HPV-16和/或18型) 单纯疱疹病毒型 人巨细胞病毒

Definition Preterm Labor: Labor occurring prior to the completion of 37 weeks' of gestation (228 weeks), or 196-258 days from the last menstrual period (LMP)

Definition Placenta previa: Abnormal location- of the placenta over,orin close proximity to the internal os. Incidence: approximately 1 /250 pregnancy nulliparas: 1/1000~1/1500 pregnancy grandmultiparas: 1/20

Definition PROM is defined as the rupture of the chorioamniotic membrane before the onset of labor

Pregnancy-induced Hypertension syndrome (Hypertensive disorders complicating pregnancy) Professor of obstetrics and gynecology

General Consideration Diabetes mellitus complicating pregnancy Diabetes mellitus is diagnosed before this pregnancy Gestational diabetes mellitus (GDM) Carbohydrate intolerance of varying degree of severity with onset or first recognition during pregnancy