In vitro maturation of Xenopus oocytes and assay of maturation-promoting factor(MPF) Progesterone Sperm

General introduction Ion channels G-protein coupled receptors Second messengers Tyrosine kinase receptors From plasma membrane to the nucleus: Regulation of gene expression Cytokine signaling Cell cycle Apoptosis

A. Symbolism of organ synthesis. B. The central question of organ synthesis. C. What is required to synthesize an organ? D. Trans-organ rules of synthesis

B. Conjunctiva synthesis in vivo (regeneration) 1. Structure and function of conjunctiva. 2. Clinical effects of conjunctival scarring. 3. Anatomically well-defined defect. 4. Synthesis of conjunctival stroma, followed by re-epithelialization

Methodology of Organ Synthesis A Skin B Conjunctiva C. Peripheral nerves D. simplest synthetic pathways

TISSUES COMPRISING JOINTS Permanent Regeneration Prosthesis Scaffold Bone

ELEMENTS FOR TISSUE REGENERATIONENGINEERING CELLS Autologous, Adult (pulp and bone marrow stromal stem cell)

TISSUES COMPRISING JOINTS Permanent Regeneration Prosthesis Scaffold

Outline 1. Irreversible injury 2. Regenerative and nonregenerative tissues 3. Antagonistic relation between contraction and regeneration 4. Present theory: Selective inhibition of contraction necessary but not sufficient for regeneration 5. Mechanism

JOINT REPLACEMENT PROSTHESES Fit -Anatomy Function -Kinematics; Range of Motion Fixation Bone cement, bone interdigitation with an irregular surface, bone ingrowth into a porous coating Tribology