CELLS FOR TISSUE ENGINEERING/REGENERATIVE MEDICINE Autologous -Differentiated parenchymal cells of same or other tissue type -Stem cells (adult) Allogeneic

SACHUSE Massachusetts Institute of Technology Harvard Medical School Brigham and Women's/Massachusetts General Hosp

biologically active model of ECM acts as an insoluble regulator of cell function image removed due to copyright considerations

The Cell and Its Membrane Molecules Plasma membrane-5nm Rough ER Smooth ER Nucleus-3-10 um Nucleolus Nuclear pore -Golgi complex Extracellular

2.4.1 Cell Activities \Packaged\ sequences (cascades) of cell activities/functions with an identifiable beginning and an end 2.4.1.1 Mitosis(Proliferation) Mitosis is a complex of processes leading to the division of a cell such that the two daughter nuclei receive identical complements of the number of chromosomes characteristic of the cells of the species. All cells arise from the division of pre-existing cells. The process of mitosis is divided into four phases:

Chapter 2. Cell-Matrix Interactions. [that determine biomaterials function in vitro and in vivo] A. How cells pull onto and deform the matrix to which they attach themselves. B. Cell-matrix interactions control the spontaneous closure of wounds in organs. C. What happens when regeneration is induced?

C. Synthesis of biologically active scaffolds (regeneration templates) 1. History of biologically active scaffolds (regeneration templates). 2. Physical chemistry of collagen: Melting of collagen quaternary structure (thromboresistance). Melting of collagen tertiary structure (gelatinization). 3. Synthesis of ECM analogs: lonic complexation

TISSUE Tissue is a biological structure made up of cells of the same type. - Cells of the same phenotype(e., same genes expressed). An aggregation of morphologically similar cells and associated extracellular matrix acting together to perform one or more specific functions in the body. - There are four basic types of tissue: muscle, nerve, epithelia, and connective. An organ is a structure made up of or more tissues

研究内容： 医学数据的交互与可视化 组织变形的模拟 感官反馈的模拟

人格概念 人格指个体在适应社会生活的成长过程中经遗传与环境交互作用而形成的独特而稳定的心身组织