General Concepts of Renal Disease 2005-3-10 Huashan hospital, Fudan University
1 General Concepts of Renal Disease 2005-3-10 Huashan hospital,Fudan University
Contents Normal anatomy, physiology and metabolism of the kidney Clinical manifestation of renal disease Diagnosis and treatment
2 Contents • Normal anatomy,physiology and metabolism of the kidney • Clinical manifestation of renal disease • Diagnosis and treatment
Anatomy of the Kidney Structure of the kidney The nephron Renal vasculature Interstitium
3 Anatomy of the Kidney • Structure of the kidney • The nephron • Renal vasculature • Interstitium
The nephron Glomerulus Bowman's capsule Tubulus
4 The nephron • Glomerulus • Bowman’s capsule • Tubulus
The glomerulus Glomerular endothelium The podocytes The mesangium The filtration barrier
5 The glomerulus • Glomerular endothelium • The podocytes • The mesangium • The filtration barrier
The filtration barrier The endothelium Glomerular basement membrane The podocyte foot process
6 The Filtration Barrier • The endothelium • Glomerular basement membrane • The podocyte foot process
Physiology of the Kidney Glomerular filtration Renal tubular reabsorption Kidney and endocrine system
7 Physiology of the Kidney • Glomerular filtration • Renal tubular reabsorption • Kidney and endocrine system
Clinical Manifestation of renal disease Edema Hypertension Flank pain Dysuria and frequency Oligulia and anuria Polyuria and nocturia Proteinuria and hematuria
8 Clinical Manifestation of Renal Disease • Edema • Hypertension • Flank pain • Dysuria and frequency • Oligulia and anuria • Polyuria and nocturia • Proteinuria and hematuria
Clinical Manifestation of renal disease Pyuria and bacilluria Renal insufficiency
9 Clinical Manifestation of Renal Disease • Pyuria and bacilluria • Renal insufficiency
Oliguria Prerenal oliguria Parenchymatous oliguria ° Postrenal oliguria
10 Oliguria • Prerenal oliguria • Parenchymatous oliguria • Postrenal oliguria