Eukaryotic Chromosomes are composed of DNA, Histone and Nonhistone Proteins Histones: H1 H2A. H2 B, H3, H4. The later 4 form nucleosomes(100 A)and thus called core histones. H1 plays a role in forming 300 A superhelix Histones are rich in basic amino acids Nonhistone proteins play a variety of functions
Parallels with Simple regression Bo is still the intercept B, to Bk all called slope parameters u is still the error term(or disturbance) Still need to make a zero conditional mean assumption, so now assume that E(lx,x2…,x)=0 Still minimizing the sum of squared residuals. so have k+l first order conditions Economics 20- Prof anderson