Introdution Morbidity and mortality The compromised host of the neonates in immunology Pathogens for clinical consideration Clinical manifestation Antibiotic therapy
Important to notice Recognize neonates with different gestational age(GA) General care for the neonates Special risks of the prematures and LBWI Importance of the initial examination after birth
Properties of herpesviruses Enveloped double stranded DNA viruses. Genome consisits of long and short fragments which may be orientated in either direction, giving a total of 4 isomers
Live difficult diagnosis clinical picture, skin biopsy, corneal impression(antibodies only appear very late) Dead- brain sent to Onderstepoort Negri bodies in cytoplasm of brain cells; immunofluorescence virus isolation