17.1 Introduction 17.2 The mating pathway is triggered by pheromone-receptor interactions 17.3 The mating response activates a G protein 17.4 Yeast can switch silent and active loci for mating type 17.5 The MAT locus codes for regulator proteins 17.6 Silent cassettes at HML and HMR are repressed 17.7 Unidirectional transposition is initiated by the recipient MAT locus 17.8 Regulation of HO expression 17.9 Trypanosomes switch the VSG frequently during infection 17.10 New VSG sequences are generated by gene switching 17.11 VSG genes have an unusual structure 17.12 The bacterial Ti plasmid causes crown gall disease in plants 17.13 T-DNA carries genes required for infection 17.14 Transfer of T-DNA resembles bacterial conjugation 17.15 Selection of amplified genomic sequences 17.16 Transfection introduces exogenous DNA into cells 17.17 Genes can be injected into animal eggs 17.18 ES cells can be incorporated into embryonic mice 17.19 Gene targeting allows genes to be replaced or knocked out
11.1 Introduction 11.2 Lytic development is divided into two periods 11.3 Lytic development is controlled by a cascade 11.4 Functional clustering in phages T7 and T4 11.5 Lambda immediate early and delayed genes are needed for both lysogeny and the lytic cycle
recognition by most T cells from recognition by B iction. In most cases, both th maturati vation of ma the involver diversity o CD4\ and CD class I MHC Activat Engagement of TcR by Peptide: MHC Initiates interaction of th n antigenic Signal Transduction tide displayed though the sp
cell receptor when complexed with MHC,are called antigens. The molecular properties of antigens and he way in which these properties ultimately contribute to immune activation are central to our understanding of the mmune system. This chapter describes some of the molecu- Complementarity of Interacting Surfaces of Antibody(left) lar features of antigens recognized by B or T cells. The chap and Antigen(rig ter also explores the contribution made to immunogenicity by the biological system of the host; ultimately the biological system determines whether a molecule that combines with a a Immunogenicity Versus Antigenicity Bor T cells antigen-binding receptor can then induce an im
October 22, 2001 Personal IdentityⅢ . Review soul criterion and body criterion Soul criterion: x is the same person as y iff and y have the same soul. Problems: i)There is no way to establish body-soul correlations; and no way to establish personality correlations. So soul criterion doesn't make sense of our practices of recognizing and identifying people ii)We have no special access to souls, so even in our own case we can't be sure it's the same soul \inside\ us whenever we are conscious. ii) The problem of identity is \pushed back\: what is it for person-stage x to have the same soul as person-stage y? What makes for sameness of souls? Body criterion: x is the same person as y iff x and y have the same living human body
