VORM LIKE 土 RIN LAS[l< F ILAMENTS s √s Bending Emrst= 2 E工 dNs.F v ERSIS TENCE Le心T计 <t(s).t(s+as))=exp △s E工 P BENDIN E NERo 2 E t见 &s 2 RELATION。= WLc E FsC <&7=2 2 P exP LC P P <R27→L ti ble KR2722PL P
dsDNa fit to WLc model Hooke’slaw 0.01 0.4 0.8 Extension(X/L) After Bustamante et al., Current Opinion in Structural Biology, 2001
FJC dsDNA 100 10 1 0.1 0.01 Hooke’s law fit to WLC model Force (pN) 0 0.2 0.4 0.6 0.8 1.0 1.2 Extension (x/L) After Bustamante et al., Current Opinion in Structural Biology, 2001
8760 Marko and Siggia (Mac rowekecules (qas) Graph( Figure 2. )removed due to copyright considerations Tep/t( 2 ds D: fficul. in Me ra Marke 4 siggi (ins): limit> for P/L L
Graph (Figure 2.) removed due to copyright considerations
Images removed due to copyright considerations See Figures 1, 2, and 3 and Table 1 in Isambert, Herve, et al Flexibility of Actin Filaments Derived from Thermal Fluctuations Journal of Biological Chemistry 270(19)12 May 1995, 11437-11444
Images removed due to copyright considerations. See Figures 1, 2, and 3 and Table 1 in Isambert, Herve, et al. "Flexibility of Actin Filaments Derived from Thermal Fluctuations." Journal of Biological Chemistry 270 (19) 12 May 1995, 11437-11444
After Fig. 1 and 2 in Sun, Y et al. "Mechanical Properties of Single Type ll Collagen Molecule Paper No: 0082, 48th Annual Meeting of the Orthopaedic Research Society Stretching a procollagen ll molecule with an optical tweezers Cover glass Procollagen Cover glass XY stage Laser light The force-extension curve of a single collagen II 50100150200150300350 Extensions(nm) Image removed due to copyright considerations Figure 1 in Fuji, T et al. "Mechanical Properties of Single Hyaluronan Molecules. Paper No: 0390, 48th Annual Meeting of the Orthopaoedic Research Society
After Fig. 1 and 2 in Sun, Y. et al. "Mechanical Properties of Single Type II Collagen Molecule." Paper No: 0082, 48th Annual Meeting of the Orthopaoedic Research Society. Image removed due to copyright considerations. Figure 1 in Fujii, T. et al. "Mechanical Properties of Single Hyaluronan Molecules." Paper No: 0390, 48th Annual Meeting of the Orthopaoedic Research Society
Modeling Extreme EXtension Ising Model Cizeau viovy 1997 Images removed due to copyright considerations
Modeling Extreme Extension: Ising Model Cizeau & Viovy 1997 Images removed due to copyright considerations
Image removed due to copyright considerations Figure 1 in Leger, J. F et al. "Reca binding to a single double-stranded DNA molecule A possible role of DNA conformational fluctuations Proc. Natl. Acad. Sci. USA-Biophysics 95 (Oct 1998)pp. 12295-12299
Image removed due to copyright considerations. Figure 1 in Leger, J. F. et al. "RecA binding to a single double-stranded DNA molecule: A possible role of DNA conformational fluctuations." Proc. Natl. Acad. Sci. USA - Biophysics 95 (Oct 1998) pp. 12295-12299
Images removed due to copyright considerations Bennink, Martin L et al. " Unfolding individual nucleosomes by stretching single chromatin fibers with optical tweezers. "Nature Structural Biology 8(7) July 2001
Images removed due to copyright considerations. Bennink, Martin L. et al. "Unfolding individual nucleosomes by stretching single chromatin fibers with optical tweezers." Nature Structural Biology 8 (7) July 2001
N EEEo>2 N SEE 三9=9三 日 是9
Pulling on Titin Sawtooth profile Image removed due to copyright considerations Figure 1 in Marszalek, Piotr E, et al. "Mechanical unfolding intermediates in titin modules Nature402,100-103(04Nov1999)
Pulling on Titin "Sawtooth profile" Image removed due to copyright considerations. Figure 1 in Marszalek, Piotr E., et al. "Mechanical unfolding intermediates in titin modules." Nature 402, 100-103 (04 Nov 1999)
