Medical Genetics 16遗传与肿瘤发生 Cancer genetics
Medical Genetics 16 遗传与肿瘤发生 Cancer Genetics
Medical Genetics The ancient greeks believed that cancer was caused by too much body fluid they called black bile
Medical Genetics The ancient Greeks believed that cancer was caused by too much body fluid they called "black bile
Medical Genetics Doctors in the seventeenth and eighteenth centuries suggested that parasites caused cancer. Today doctors understand more about the ink between cancer and genetics
Medical Genetics Doctors in the seventeenth and eighteenth centuries suggested that parasites caused cancer. Today, doctors understand more about the link between cancer and genetics
Medical Genetics Viruses, ultraviolet (Uv) radiation, and chemicals can all damage genes in the human body. If particular genes are affected a person can develop cancer. Understanding how genes cause cancer though, first requires a basic understanding of several genetic terms and concepts
Medical Genetics Viruses, ultraviolet (UV) radiation, and chemicals can all damage genes in the human body. If particular genes are affected, a person can develop cancer. Understanding how genes cause cancer, though, first requires a basic understanding of several genetic terms and concepts
Medical Genetics 1 General Cancer is a very common disease, affecting about 1 in 3 individuals, and about half the people that contract cancer will die as a direct result of their disease
Medical Genetics 1. General Cancer is a very common disease, affecting about 1 in 3 individuals, and about half the people that contract cancer will die as a direct result of their disease
Medical Genetics Tumors are hereditary Hereditary retinoblastoma is an autosomal dominant trait in which susceptibility to retinoblastoma is inherited. This is an unusual dominant trait in that a mutation in one rb gene is not sufficient to cause symptoms, but mutations in the second allele often arise during development
Medical Genetics Tumors are hereditary Hereditary retinoblastoma is an autosomal dominant trait in which susceptibility to retinoblastoma is inherited. This is an unusual "dominant" trait in that a mutation in one RB gene is not sufficient to cause symptoms, but mutations in the second allele often arise during development
Medical Genetics
Medical Genetics
Medical Genetics The mutations occur after birth and result in tumor formation Tumors usually develop in only one eye and patients are not at high risk for other cancers both alleles need to be mutated in a single cell, and that is why this form typically occurs only in one eye
Medical Genetics The mutations occur after birth and result in tumor formation. Tumors usually develop in only one eye and patients are not at high risk for other cancers. Both alleles need to be mutated in a single cell, and that is why this form typically occurs only in one eye
Medical Genetics Hereditary Spora retinoblastoma relinoblastoma First Mutation RB I atation utation HB目RB Retinoblastoma Retinoblastoma a
Medical Genetics
Medical Genetics Chromosome and tumors Detailed studies of the philadelphia chromosome show that most of chromosome 22 has been translocated onto the long arm of chromosome 9. In addition the small distal portion of the short arm of chromosome 9 is translocated to chromosome 22. this translocation, which is found only in tumor cells indicates that a patient has chronic myelogenous leukemia(CML). In CML, the cells that produce blood cells for the body(the hematopoietic cells grow uncontrollably, leading to cancer
Medical Genetics Chromosome and tumors Detailed studies of the Philadelphia chromosome show that most of chromosome 22 has been translocated onto the long arm of chromosome 9. In addition, the small distal portion of the short arm of chromosome 9 is translocated to chromosome 22. This translocation, which is found only in tumor cells, indicates that a patient has chronic myelogenous leukemia (CML). In CML, the cells that produce blood cells for the body (the hematopoietic cells) grow uncontrollably, leading to cancer
