Medical Genetics 04基因突变的分子 细胞生物学效应 cellular effects of gene mutation
Medical Genetics 04 基因突变的分子 细胞生物学效应 cellular effects of gene mutation
Medical Genetics 1. Genes can be mutated in many ways The most common gene change nvolves a single base mismatch--a misspelling--placing the wrong base in the dNA. at other times a single base may be dropped or added And sometimes large pieces of DNA are mistakenly repeated or deleted
Medical Genetics 1.Genes can be mutated in many ways The most common gene change involves a single base mismatch--a misspelling--placing the wrong base in the DNA. At other times, a single base may be dropped or added. And sometimes large pieces of DNA are mistakenly repeated or deleted
Medical Genetics Gene Mutations Mismatch Deletion Repetition Deletion
Medical Genetics
Medical Genetics When a gene contains a mutation the protein encoded by that gene is likely to be abnormal
Medical Genetics When a gene contains a mutation, the protein encoded by that gene is likely to be abnormal
Medical Genetics DNA→>RNA→> Protein Cell DNA Nucleus membrane Chain of DNA amIno bases mRNA acids Ge ene Protein Ribosome
Medical Genetics
Medical Genetics Altered dnA->Altered protein cell DNA Nucleus membrane Chain of amino DNA acids bases mRNA. 端 Protein Ribosome
Medical Genetics
Medical Genetics 2. Somatic versus germline mutations Gene mutations can be either nherited from a parent or acquired
Medical Genetics 2. Somatic versus germline mutations Gene mutations can be either inherited from a parent or acquired
Medical Genetics Somatic tissue orma progeny Germinal tissue Mutant \ sector Mutant sector Norm Mutant progeny progeny
Medical Genetics
Medical Genetics Hereditary mutations are carried in the dna of the reproductive cells. When reproductive cells containing mutations combine to produce offspring, the mutation will be in all of the offspring's body cells
Medical Genetics Hereditary mutations are carried in the DNA of the reproductive cells. When reproductive cells containing mutations combine to produce offspring, the mutation will be in all of the offspring's body cells
Medical Genetics The fact that every cell contains the gene change makes it possible to use cheek cells or a blood sample for gene testing
Medical Genetics The fact that every cell contains the gene change makes it possible to use cheek cells or a blood sample for gene testing