EDEMAPathophysiologyDepartment, ShiHeZiMedical College,HUsT
Pathophysiology Department, ShiHeZi Medical College, HUST
488688ascitesIncreasedamountoffluidbetweenabdominal structuresLungPulmonaryedemaAccumulation offluid intheair sacs (alveoli)in the lungs
ascites Pulmonary edema
EdemaDefinition Pathogenesis Treatment
Edema • Definition • Pathogenesis • Treatment
Edema is defined as soft tissue swellingdue to expansion of the interstitial volume
Edema is defined as soft tissue swelling due to expansion of the interstitial volume
Pathogenesis★ Disturbance of Transcapillary Fluid Exchange★ Sodium and Water Retention
Pathogenesis ★ Disturbance of Transcapillary Fluid Exchange ★ Sodium and Water Retention
CapillaryPc=capillaryhydrostaticpressureP-=tissuehydrostaticpressureFiltrationReabsorptionTe=capillaryplasmaoncoticpressure元=tissuefluidoncoticpressureLymphFlowTerminal Lymphatic元cPc元T25mmHg20mmHg1-10mmHg15mmHg
Pc 20mmHg PT -10mmHg T 15mmHg C 25mmHg + - ﹝ + ﹞ 〉0
个CapillaryHydrostaticPressureInterstitialFluidVenousHydrostaticArterialOncoficendendpressurepressure20ydrostaticHydrostaticpressure18pressure37OncoticpressureCapillaryeg: thrombophebitis, hepatic obstruction, tight clothingaroundtheextremities,prolongedstanding
↑Capillary Hydrostatic Pressure eg: thrombophebitis, hepatic obstruction, tight clothing around the extremities, prolonged standing
ICapillaryPlasmaColloidOsmoticPressureInterstitial FluidVenousHydrostaticArterialOncoticendendpressurepressure20drostatidHydrostaticpressure18pressure37OncoticpressureCapillaryeg: glomerular diseases of the kidney,serous drainagefromopenwounds,burns,cirrhosisoftheliver
↓Capillary Plasma Colloid Osmotic Pressure eg: glomerular diseases of the kidney,serous drainage from open wounds,burns,cirrhosis of the liver
TissueFabMeHoReaagadtintpressureInterstitialFluidVenousHydrostaticArterialOncoticendendpressurepressure2OydrostaticHydrostaticpressure18pressure37Oncoticpressure25Capillaryeg:Severe inflammation
↑Tissue Fluid Colloid Osmotic Pressure eg: Severe inflammation ↑Capillary Permeability
Obstructionof LymphaticReturnCapillaryFiltrationReabsorptionLymphFlowTerminal Lymphatic
Obstruction of Lymphatic Return