分子细胞生物学 Molecular CELL biology 主讲教师:丁明孝,陈建国,张传茂
分子细胞生物学 Molecular CELL BIOLOGY 主讲教师：丁明孝，陈建国，张传茂
Chapter 1 Introduction to the celll Learning Objectives 1. About Cell biology 2. Look briefly at the history of cell theory 3. Consider the basic properties of cells 4. Compare some characteristics of two different classes of cells prokaryotes and eukaryotes 5. Comprehend a special life: viruses
Chapter 1 Introduction to the cell Learning Objectives 1.About Cell Biology 2.Look briefly at the history of cell theory; 3.Consider the basic properties of cells; 4.Compare some characteristics of two different classes of cells: prokaryotes and eukaryotes; 5.Comprehend a special life: viruses
1. About“ Cell Biology The nih of usa(1988): What? “ What is popular in research today?” ◆3 kinds of diseases: cancer o cardiovascular diseases Forwhy? o infectious diseases: AIDS, hepatitis ◆5 research fields ◇ cell cycle control; How to ◇ cell apoptosis ◇ cellular senescence; study signal transduction ◇ dNA damage and repair What we know/How we know
1. About “Cell Biology” What? Forwhy? How to study? The NIH of USA(1988): “What is popular in research today？” 3 kinds of diseases ： cancer cardiovascular diseases infectious diseases：AIDS，hepatitis 5 research fields ： cell cycle control； cell apoptosis； cellularsenescence； signal transduction； DNA damage and repair. What we know//How we know
ISI, USA(1997): SCI (Science Citation Index) Papers: Three tops of research fields Nol: Signal transduction; No2: Cell apoptosis; No3: Genome and post-genomic analysis
ISI, USA(1997) : SCI（Science Citation Index）Papers: Three tops of research fields: No1: Signal transduction； No2: Cell apoptosis； No3: Genome and post-genomic analysis
2. The Cell Theory: A Brief history The discovery of cells followed from the invention of the microscope In 1665. Robert Hooke saw a network of tiny boxlike compartments that reminded him of a honeycomb. He called these little compartments“ cellulae”,a Latin term meaning little room. It K is from this word we get our present-day term, cell. The microscope used by Robert Hooke and the honeycomb-like network of“cel” he drawed in1665
2. The Cell Theory: A Brief History In 1665, Robert Hooke saw a network of tiny boxlike compartments that reminded him of a honeycomb. He called these little compartments “cellulae”, a Latin term meaning little room. It is from this word we get our present-day term, cell. The microscope used by Robert Hooke and the honeycomb-like network of “cell” he drawed in 1665 The discovery of cells followed from the invention of the microscope
Cell theory has three basic tenets 1. All organisms are composed of one or more cells 2. The cell is basic unit of structure and function for all organIsms. 3. All cells arise only 区19. Schleiden(1804~1834) M 20.Schwann(1510-18s from preexisting cells by division
Cell theory has three basic tenets: 1. All organisms are composed of one or more cells. 2.The cell is basic unit of structure and function for all organisms. 3.All cells arise only from preexisting cells by division
3. Why are cells the basic units of life? A. The cell is the structural unit of life All organisms is make up of cells Doh mussa IntesTinal ermhnt al cers
3. Why are cells the basic units of life? A. The cell is the structural unit of life, All organisms is make up of cells
BThe cell is the functional unit of organisms All meta bolic activity is based on cells
B.The cell is the functional unit of organisms. All metabolic activity is based on cells
The cell is the foundation of reproduce and the bridge of inheritance
C. The cell is the foundation of reproduce, and the bridge of inheritance
D. The cell is the growing and developing basis of life I cm long 6 cm long 30 cm in length )5 weeks (b)14 weeks (c)20 weeks Human fetal development. (a)At 5 weeks, limb buds, eyes, the heart, the liver and rudiments of all other organs have started to develop in the embryo, which is only about lcm long. (b)Growth and development of the offspring, now called a fetus continue during the second trimester. This fetus is 14 weeks old and about 6cm long(cThe fetus in this photograph is 20 weeks old. Now the fetus grows to about 30cm in length
D. The cell is the growing and developing basis of life Human fetal development. (a)At 5 weeks, limb buds, eyes, the heart, the liver and rudiments of all other organs have started to develop in the embryo, which is only about 1cm long. (b)Growth and development of the offspring, now called a fetus, continue during the second trimester. This fetus is 14 weeks old and about 6cm long. (c)The fetus in this photograph is 20 weeks old. Now the fetus grows to about 30cm in length