ASTHMA ECZEMA Michael Widjaja 08301016030 黄合乐
ASTHMA, ECZEMA Michael Widjaja 08301016030 黄合乐
UTlIne 口 Preconceived notions a How allergic asthma is triggered 口 Mechanism of asthma a Methods of treatment of asthma o Factors that lead to asthma 口 Eczema and the factors that lead to计 o Link between asthma and eczema 口 Conclusion
Outline Preconceived notions How allergic asthma is triggered Mechanism of asthma Methods of treatment of asthma Factors that lead to asthma Eczema and the factors that lead to it Link between asthma and eczema Conclusion
Initial thoughts on asthma n Asthma causes difficulty in breathing 口 Consists of two parts a Constriction of bronchi a Overproduction of mUcuS in respiratory tract 口 Caused by 口 Allergies a Drastic change in temperature a Exercise a Heritable family history
Initial thoughts on asthma Asthma causes difficulty in breathing Consists of two parts Constriction of bronchi Overproduction of mucus in respiratory tract Caused by Allergies Drastic change in temperature Exercise Heritable? family history
Initial thoughts on Eczema a Dry itchy skin, redness, cracking, oozing or bleeding n causes 口 Allergies a Skin Irritants a Dry weather a Sweat n Eczema linked to asthma in some way a Genetically linked disease?
Initial thoughts on Eczema Dry itchy skin, redness, cracking, oozing or bleeding Causes Allergies Skin Irritants Dry weather Sweat Eczema linked to Asthma in some way Genetically linked disease?
Anatomy of Asthma moored at个 expired a Anatomy of an Asthma Attack primary breech larynx (voice boo) trachea (windpipe) rgnt lng left wng bronotxlos ranchi tube biood vesels filtrated by inflammation mmre cels and selling decre→sed contr acted lmon smooth esoo mcu amooth Dood vessels lumen 6 2001 Encyclopaedia Britannica, ino normal airway bstruoted airway
Anatomy of Asthma
Triggers of Asthma Dust 口 Pollen 口 Cockroaches 口 Cold air a Smoke a Animal dander, skin dried saliva, hair
Triggers of Asthma Dust Pollen Cockroaches Cold air Smoke Animal dander, skin, dried saliva, hair
Mast cells and plasma Cells Muscle cell Blood vessel Plasma cells he Villar epitheliu
Mast Cells and Plasma Cells
Mechanism of asthma 口 Antigen enters body n Plasma cell produce immunoglobulin e(lge d ige binds to surface of mast cells n Future exposures to antigen results in binding of antigen to surface bound igE a Mast Cells degranulate releasing Histamine and Leukotriene
Mechanism of Asthma Antigen enters body Plasma cell produce immunoglobulin E(IgE) IgE binds to surface of mast cells Future exposures to antigen results in binding of antigen to surface bound IgE Mast Cells degranulate releasing Histamine and Leukotriene
Mast Cell degranulation Adenylate cyclase Fusion of granules Micro filaments ECF-A
Mast Cell Degranulation
Steroid effects of the lung a Leukotriene promotes contraction of smooth muscle of the bronchioles n Histamine increases vascular permeability, causing capillary eakage and edema Why asthma makes it hard to breathe ed bronchial tube Normal bronchial tube
Steroid effects of the lung Leukotriene promotes contraction of smooth muscle of the bronchioles Histamine increases vascular permeability, causing capillary leakage and edema