《医学遗传学 Medical Genetics》课程教学资源（教学大纲）

1.Genes can be mutated in many ways The most common gene change involves a single base mismatch--a misspelling--placing the wrong base in the DNA. At other times, a single base may be dropped or added. And sometimes large pieces of DNA are mistakenly repeated or deleted

Some disorders result when a mutation causes the product of a single gene to be altered or missing. These disorders are inherited in simple patterns similar to or identical with those described by Mendel for certain discrete characteristics in garden peas. Therefore, it’s also called Mendelian diseases

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods

Stage 1: Warming-up Activities Stage 2: Reading-Centred Activities Stage 3: After-Reading Activities Stage 4: Listening-and-Speaking Practice

一．遗传学的基本概念 二．遗传学研究的范围和任务 三．遗传学发展概况 四．遗传学的应用

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods

Bacterial genomics Organisation Linear chromosomes Borrelia burgdorferi Streptomyces coelicolor Multiple chromosomes Vibrio cholerae Plasmids Borrelia burgdorferi

麻省理工大学：遗传学（Genetics）讲稿_lecture35