insolubility. Administration of cystamine, a transglutaminase inhibitor, reduces the To date, 10 neurological diseases, including aggregate formation, retarding the Huntington's and several ataxias, are caused development of neurological phenotype and by the lengthening of glutamine(@) tracts in prolonging the life span of brain cells in various proteins with no obvious functional or transgenic mouse models

PROTACS: CHIMERIC MOLECULES TO TARGET PROTEINS FOR UBIQUITINATION AND (taken from KM Sakamoto, Mol. Genetics and Metabolism 77(2002)44-56) target targettargettarget target target target target target To circumvent the problem of transducing cells at

Unit 2 English Reserve and politeness I Objective Aware of the Characteristics of the English people A Figuring out general British personalities A Learning about headline Vocabulary Time arrangement Text:2 hours

Reversible ligation of Ubiquitin and Ubls to other proteins. Figure by MIT OCW. After Figure 1 in Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000 Aug:

HAANSTRA. Bert 1952 Dijkbourw( Dike Builders)(+ sc, ed) 1954 Ont staan en vergaan (The Changing Earth)(+ sc); De Nationality: Dutch. Born: Holten, Holland, 31 May 1916. Educa- opsporing van aardolie (The Search for Oil)(+ sc); De tion: Academy of Arts, Amsterdam. Career: Painter and press erkenningsboring(The Wildcat)(+ sc) Het olieveld (The Oilfield)(+ sc) photographer, from late 1930s; joined

Michelle Banks, Erin Bealmear, Laura Standley Berger, Joann Cerrito, Jim Craddock, Steve Cusack, Nicolet V. Elert, Miranda H. Ferrara, Kristin Hart Melissa Hill, Laura S Kryhoski, Margaret Mazurkiewicz, Carol Schwartz, and Christine Tomassini, St James Press Staff laria Franklin, Permissions Manager Debra J. Freitas. Permissions assistant Mary Grimes, Leitha Etheridge-Sims, Image Catalogers

People send information in three steps and through two types of memory, short term and long term. Physical experiments on short-term memory are carried out. They indicate that even slight delays or interruption can prevent information from being

10-1: Inflation, Expected Inflation, and Unemployment 10-2: The Phillips Curve 10-3: A Summary and many Warnings

Process Control plants 16.422 Continuous or batch processing Examples: Electricity generation(nuclear power plants), refineries, steel production, paper mills, pasteurization of milk Characterized by Large scale, both physically and conceptually Complex

6-1: Openness in Goods Market 6-2: Openness in Financial Market 6-3: Conclusions and a Look ahead