Lecture 11: Molecular Design and Synthesis of Biomaterials Il: Inorganic Biomaterials Last time: hydrogel applications: molecular imprinting and responsive drug delivery Today biomineralization and biomimetic inorganic/organic composites Inorganic biomaterials Reading L A. Estroff and A D. Hamilton, ' At the interface of organic and inorganic chemistry
1. (4 pts) An early study in the development of peptide-presenting biomaterials showed that polymer surfaces bearing RGD peptides at a density equivalent to -10 peptides per each cell was sufficient to promote cell attachment, spreading and subsequent cell growth. In contrast, when whole fibronectin protein was adsorbed to polymer surfaces, it was found that many more copies of the