A group of diseases Pathological changes glomerular injury Clinical manifestations --proteinuria/ hematuria Comp/icated causes& mechanisms Various clinical manifestations Different prognosis Multiple treatment
Background Sedative-hypnotics are a group of drugs that cause cns depression Benzodiazepines(Bzd) the most commonly a barbiturates used agents nonbarbiturate nonbenzodiazepine sedative hypnotics(NBnB)
Summarization Definition: serum total bilirubin(STB)> 34umol/L. causing a yellow color of skin. sclera and tissue fluid Latent icterus: an increase of stb but not more than 34umol/L, without color changes of skin and sclera
Epidemiology 6th leading cause of death in U.S. Number one Among the infectious diseases 6 million patients annually in US Incidence 5~10/1,000/year Mortality in OPD patients 1-5 % but Inpatients 25%, ICU 50-60%
DIAGNOSIS AND CLASSIFICATION Anemia is an absolute decrease in hematocrit, hemoglobin concentration,or the RBC count. Anemia is not a diagnosis, but a sign of underlying disease
Classification of diabetes(ADA -1997) Type 1 .(beta-cell destruction, usually leading to absolute insulin deficiency) Autoimmune Idiopathic Type2 (may range from predominantly insulin resistance with relative insulin deficiency to a predominantly secretory defect with or without insulin resistance)