Chapter Two Tissue injury Section A Cellular adaptation. Atroph Hypertrophy Hyperplasia Metaplasia
Cellular adaptation: Atrophy Hypertrophy Hyperplasia Metaplasia Chapter Two Tissue injury
CELLULARADAPTATION Excessive physiologic stresses Some pathologic stimuli. a new, but altered state preserving the viability of the cell
CELLULAR ADAPTATION • Excessive physiologic stresses. • Some pathologic stimuli. A new, but altered state preserving the viability of the cell
ATROPHY Decrease in mass of the cell HYPERTROPHY Increase in mass of the cell
ATROPHY Decrease in mass of the cell HYPERTROPHY Increase in mass of the cell
ATROPHY ● Decreased workload Loss of innervation。 Diminished blood supply. Inadequate nutrition. Loss of endocrine stimulation aging
ATROPHY • Decreased workload. • Loss of innervation. • Diminished blood supply. • Inadequate nutrition. • Loss of endocrine stimulation. • Aging
Morphology of atrophy Brown atrophy Reduction in the number of cell organelles Increase in the number of autophagic vacuoles。 Lipofuscin granules(Brown atrophy
Morphology of atrophy Brown atrophy Reduction in the number of cell organelles. Increase in the number of autophagic vacuoles. Lipofuscin granules (Brown atrophy)
正常胸腺 萎缩胸腺 ,然∵的牙
Fig 2-5
正常心脏 萎缩心脏
心肌褐色萎缩
正常心肌 萎缩心肌
心肌褐色萎缩
