BLOOD9O080
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ContentsBloodPlasmaBloodcellsBloodplateletsHematopoiesis
Plasma Contents Blood cells Blood Blood platelets Hematopoiesis
ConstructionPlasma (intercellularPlasmamatrix) : 55%Hemocytes (cells): 45%erythrocytes RBCLeucocytesleucocytes WBC&Platlets blood plateletshematocrit (packed red cellvolume): 45%Erythrocytes*using anticoagulants
Construction Construction Plasma (intercellular matrix) : 55% Hemocytes (cells)：45% erythrocytes RBC leucocytes WBC blood platelets • hematocrit (packed red cell volume): 45% Plasma Leucocytes & Platlets Erythrocytes *using anticoagulants
101010999888Plasma7I755%66Serum6555Leukocytes&44platelets333Erythrocytes2245%-Clotting211*using anticoagulants*withoutheparin*centrifugationanticoagulants
*without anticoagulants ——Serum ——Clotting *using anticoagulants heparin *centrifugation Leukocytes & platelets 55% 45%
PlasmaSerumSamecomponents90% waterwithout fibrinogen10% others :fibrinogen → fibrinplasma pr.c albuminfibrinogenenzymesserumIg.etc.PlasmalipidhormonesVitaminsbloodclotsinorganic saltsmetabolites
90% water 10% others : plasma pr. albumin fibrinogen enzymes Ig. etc. lipid hormones Vitamins inorganic salts metabolites Same components without fibrinogen serum Serum Plasma blood clots fibrinogen fibrin Plasma
Bloodcellsbloodsmearstains withWrightorGiemsa080
blood smear blood smear stains with Wright or Giemsa stains with Wright or Giemsa Blood cells
Erythrocytes>biconcavedisc,7.5μmno nuclei, no organelles>hemoglobin:（Hb）transporting&binding O, and CO2 carbon monoxideflaxible>bloodgroup(ABO)agglutinogen>lifespan:120dGroupAGroupBGroupABGraupoRad bloo>normalconcentrationcelltypefemale:3.9-5.5X106/uL祥恭茶Artibodlkmale:4.1-6X10%/μLpresemtAnd-BAn-ANeneAnd-andAnAntigenaAaridEAantigenBantigenpresentNoneartleens
biconcave disc, 7.5μm no nuclei，no organelles hemoglobin: （Hb）transporting & binding O2 and CO2 carbon monoxide flaxible blood group (ABO) agglutinogen life span: 120 d normal concentration female: 3.9-5.5×106/μL male: 4.1-6×106/μL Erythrocytes
MedicalApplication>Anemia: R.B.CErythrocytosis:anisocytosis>macrocytes>9μm; microcytes hereditary spherocytosis: defects inspectrin molecule;easytobedestructed by macrophages
Medical Application Anemia ：R.B.C 9 μm; microcytes < 6 μm; anisocytosis Sickle cell disease: caused by a mutation of one nucleotide. the triplet GAA for glutamic acid is changed to GUA for valine hereditary spherocytosis: defects in spectrin molecule; easy to be destructed by macrophages
ReticulocytesimmatureRBC,justreleasedfrombonemarrow1% of the total number of erythrocytes3-6%in newbornresidual ribosome--- netlike structure(brilliant cresyl blue)Increase in anemia indicator ofhematopoietic capacityofthebonemarrow
Reticulocytes immature RBC, just released from bone marrow 1% of the total number of erythrocytes, 3-6% in newborn residual ribosome- netlike structure (brilliant cresyl blue) Increase in anemia indicator of hematopoietic capacity of the bone marrow
LeukocytesSpherical,nucleate&colorless,6000---10.000/uLClassification:based on specific granules andnonspecificlazurophilic granulesneutrophil: 60 ~ 70%eosinophil: 2 ~ 4%Granulocyte65-70%basophil: 0.5%lymphocyte:28%Agranulocytemonocyte: 5%30-35%
Spherical, nucleate & colorless, 6000-10,000/μL Classification: based on specific granules and nonspecific/azurophilic granules Granulocyte Agranulocyte neutrophil：60～70% eosinophil：2～4% basophil：0.5% lymphocyte：28% 30-35% monocyte：5% 65-70% Leukocytes