Chapter 9Circulatory system
Chapter 9 Circulatory system
I .Concepts of organ and system@ Organ:composed of four kinds of the tissuesin a particular wayHollow organs: studied from inside to outsideypesCT. capsuleSubstantial organs:parenchyma@ System:composed of many organswhichhave relationship witheach otherinstructure and function
I .Concepts of organ and system Organ: composed of four kinds of the tissues in a particular way Types Hollow organs: studied from inside to outside Substantial organs: CT. capsule System: composed of many organs which have relationship with each other in structure and function. parenchyma
Il .Composition of circulatory systemCardiovascularsystemcapillaries,arteries,veinsand heartlymphvascularsystemlymphaticduct,lymphaticvessel,lymphatic capillary
II .Composition of circulatory system Cardiovascular system capillaries, arteries, veins and heart lymph vascular system lymphatic duct, lymphatic vessel, lymphatic capillary
1. Capillary (Cap.)AO3Distributions:broadlyandhavearelation withmetabolism.Size:Cap.generally is 6~8 μm, but some sinusoidcan reach
1. Capillary (Cap.) Distributions：broadly and have a relation with metabolism. Size：Cap. generally is 6～8 μm, but some sinusoid can reach
Basal lamina() General structures (LM)FenestraeCapillaryWallCell#1endotheliaPartofcapillarywallCell #3basallaminaLUMENpericytesPartofcapillarywallcell #2PERICYTEBasementMembrane
• endothelia (1) General structures (LM) • basal lamina • pericytes
(2)Classification(EM)Depending on the continuity of both the endothelial sheetand thebasal lamina,divided into3types:Continuous capillaryFenestratedcapillarySinusoidal capillary
(2) Classification (EM) Depending on the continuity of both the endothelial sheet and the basal lamina, divided into 3 types: Continuous capillary Fenestrated capillary Sinusoidal capillary
a. continuous capillary:ContinuouscapillaryBasementEndothelialcell membranejunctionuANucleusTrancytosisvesiclesEndothelialcellsbeneathbasementmembrane
a. continuous capillary:
tight junction*Endothelialprojections*Plasmalemmalvesicles:the pinocytotic vesiclesforlargemoleculetrans-cellmembranetransportation.transendothelialchannels*Enzymesystem
* tight junction * Endothelial projections * Plasmalemmal vesicles: the pinocytotic vesicles for large molecule transcell membrane transportation. transendothelial channels * Enzyme system
Weibel-Paladebody*Endotheliacontain specialtubular organelle,the Weibel-NPalade(WP)bodies, whichreleaseFactorVilll relatedantigen tofacilitatebloodclotting whenblood vesselsbreak.7* Distribution:muscle tissue,connective tissue
* Endothelia contain special tubular organelle, the WeibelPalade (WP) bodies, which release Factor VIII related antigen to facilitate blood clotting when blood vessels break. * Distribution: muscle tissue, connective tissue
b.fenestrated capillary:FenestratedcapillaryTrancytosis vesiclesuFenestrationsFenestratedorporesporesUDBasementEndothelialcellmembrane(cut)junctionBasementmembrane
b. fenestrated capillary: