E Membranes E1 Membrane lipids E2Membrane protein and carbohydrate E3 Membrane transport: small molecules E4. Membrane transport: macromolecules E5.Signal transduction
• E1.Membrane lipids • E2.Membrane protein and carbohydrate • E3.Membrane transport:small molecules • E4.Membrane transport:macromolecules • E5.Signal transduction E Membranes
E1 Membrane lipids Membranes Membrane lipids Fatty acid chains Lipid bilayer Membrane fluidity Fluid mosaic model of membrane structure
Membranes Membrane lipids Fatty acid chains Lipid bilayer Membrane fluidity Fluid mosaic model of membrane structure E1 Membrane lipids
Membrane Membranes form boundaries around the cell and around distinct subcellular compartments. They act as selectively permeable barriers and are involved in signaling processes. All membranes contain varying amounts of lipid and protein and some contain small amounts of carbohydrate
Membrane • Membranes form boundaries around the cell and around distinct subcellular compartments. • They act as selectively permeable barriers and are involved in signaling processes. • All membranes contain varying amounts of lipid and protein and some contain small amounts of carbohydrate
Membrane 272 Outer face Phospholipid Fatty acyl Carbohydrate moiety Cholesterol Inner face
Membrane
Membrane lipids Three major classes of lipids 1. The glycerophospholipids,甘油磷脂 2. The sphingolipids鞘脂 3. The sterols胆固醇
Membrane lipids Three major classes of lipids: 1. The glycerophospholipids,甘油磷脂 2. The sphingolipids鞘脂 3. The sterols胆固醇
Membrane lipids Outer face of bilayer Total phospholipid 50 Sphingomyelin 30 Phosphatidylcholine 20 答10 20 Phosphatidylethanolamine Phosphatidylserine oO Phosphatidylinositol Inner face of bilayer
Membrane lipids
容| Triacylglycerol三酰甘油 CHCH 互o OH OH Glycerol ICH CH -CH 1-Stearoyl, 2-linoleoyl, 3-palmitoyl glycerol a mixed triacylglycerol
Triacylglycerol三酰甘油
Phosphatidylcholine磷脂酰胆碱 CHe CH. 0=P-O CH O CH CHo-o CH-N—CH2 CHs Phosphatidylcholine
Phosphatidylcholine磷脂酰胆碱
Phosphatidate R Acyl groups C CH 2 with fatty acid hydrocarbon chains R 0O-C-H o H2O Phosphatidate (Diacylglycerol 3-Phosphate)
Phosphatidate
Glycerophospholipids 00-C oo HC NHs HC CH Coo Phosphatidyl serine Phosphatidyl choline 0 O-C-H o R OO- H O HC NH3+ HC hosphatidyl ethanolamine hosphatidyl inositol HC 00—c-HO HC Diphosphatidyl glycerol (cardiolipin)
Glycerophospholipids
