Chapter 15 Gastrointestinal System Dr.LL Wang E-mail:wanglinlin@zju.edu.cn Rm 608,Block B.Research Building.School of Medicine,Zijingang Campus
Chapter 15 Gastrointestinal System Dr. LL Wang E-mail: wanglinlin@zju.edu.cn Rm 608, Block B, Research Building, School of Medicine, Zijingang Campus
Gastrointestinal System .1.G.I.Physiology:general organization of G.I.tract 2.Mastication and deglutition ·3.Gastric secretion 4.Regulation of gastric secretion 5.Pathophysiology of peptic ulcer .6.Biliary and pancreatic secretions 7.Physiology of colon .8.Pathophysiology of diarrhea disease
Gastrointestinal System • 1. G.I. Physiology: general organization of G.I. tract • 2. Mastication and deglutition • 3. Gastric secretion • 4. Regulation of gastric secretion • 5. Pathophysiology of peptic ulcer • 6. Biliary and pancreatic secretions • 7. Physiology of colon • 8. Pathophysiology of diarrhea disease
rynx ut Gastrointestinal System includes Gl tract plus the accessory organs. Cecum Rectum Anatomy of Gastrointestinal System
Anatomy of Gastrointestinal System Gastrointestinal System includes GI tract plus the accessory organs
Four processes carried out by the Gl tract CopyrightThe McGraw-Hill Companies,Inc.Permission required for reproduction or display. Blood flow Mouth Fooiend Digestio Esophagus Small intestine Stomach Colon Motility Functions of Gastrointestinal System
. Four processes carried out by the GI tract Functions of Gastrointestinal System
hs of System Many functions in the gut are found in specific locations along its length.Most of the absorption of nutrients occurs in the small intestine,so most of digestion is accomplished there or upstream.p576
Overview:Functions of Gastrointestinal System Many functions in the gut are found in specific locations along its length. Most of the absorption of nutrients occurs in the small intestine, so most of digestion is accomplished there or upstream. p576
Copyright The McGra-Hll Companies,inc.Perm Common hepatic duct n bile duc Pancreatic duct 8Pbiater Duodenum Digestive secretions from the liver and the pancreas are delivered into the duodenum of the small intestine through the sphincter of Oddi
Digestive secretions from the liver and the pancreas are delivered into the duodenum of the small intestine through the sphincter of Oddi
Functions of small intenstine movements Mixes the luminal contents with secretions Brings the contents nto contact with the epithelial surface Slowly advances the luminal material toward the large intenstine
Functions of small intenstine movements • Mixes the luminal contents with secretions • Brings the contents nto contact with the epithelial surface • Slowly advances the luminal material toward the large intenstine
1200 ml water/day:800 g solids/day ingested 1500 ml salivary secretions Digestive secretions 2000 ml gastric secretions are mostly water, with the average amounts indicated 500 ml bile here.Note that only 6700ml 100 ml are excreted in feces,so the ntestine 500 ml pancreatic secretions mechanisms for water absorption are efficient 1500 ml intestinal secretions (primarily small intestine) (recall the kidneys' primary role in water and 140nm0bbe 1500ml osmotic homeostasis). (large intestine) Feces 100 ml water:50g solids excreted
Digestive secretions are mostly water, with the average amounts indicated here. Note that only 100 ml are excreted in feces, so the mechanisms for water absorption are efficient (recall the kidneys’ primary role in water and osmotic homeostasis)
Structure of the GI Tract Wall Tunics Serosa Muscularis (outer layer) Muscularis (inner) Submucosa Mucosa mesentery
Structure of the GI Tract Wall
Copyright The McGraw-Hill Companies,in o reproduction Abdominal cavity The gut wall has a layered organization,with the absorptive cells lining the lumen and neural and muscular components below.Blood and lymph vasculature is abundant to transport absorbed nutrients
The gut wall has a layered organization, with the absorptive cells lining the lumen and neural and muscular components below. Blood and lymph vasculature is abundant to transport absorbed nutrients