HUMAN PHYSIOLOGY Chapter 3 Blood Ying-ying Chen,PhD Dept.of Physiology,Zhejiang University School of Medicine bchenyy@zju.edu.cn
Ying-ying Chen, PhD Dept. of Physiology, Zhejiang University School of Medicine bchenyy ＠zju.edu.cn HUMAN PHYSIOLOGY HUMAN PHYSIOLOGY Chapter 3 Chapter 3 Blood
Functions of blood Transportation (gases,nutrients,hormones, wastes) Regulation(pH,fluid and ion balance, thermoregulation Protection(immune response,clotting)
Functions of blood Transportation (gases, nutrients, hormones, wastes) Regulation (pH, fluid and ion balance, thermoregulation ) Protection (immune response, clotting)
Components of blood Plasma Formed elements Plasma Buffy Coat Blood Red Blood cells Cells
Components of blood Plasma Formed elements Blood cells
Plasma mostly water(90%by volume) proteins(8%by weight) small solutes:electrolytes,lactic acid, urea
mostly water (90% by volume) proteins (8% by weight) small solutes: electrolytes, lactic acid, urea Plasma
Plasma proteins Albumins(60-80%of plasma proteins) ·transport maintenance of osmotic balance ÷Globulins(a,B-,Y-） transport of materials through the blood ·clotting factors Fibrinogen important in clotting
Plasma proteins Albumins (60-80% of plasma proteins) • transport • maintenance of osmotic balance Globulins ( α-, β-, γ-) • transport of materials through the blood • clotting factors Fibrinogen • important in clotting
Difference between serum and plasma Serum is plasma from which fibrinogen and other proteins involved in clotting have been removed as a result of clotting SERUM CLOTTED —BLOOD
Difference between serum and plasma \Serum is plasma from which fibrinogen and other proteins involved in clotting have been removed as a result of clotting
Formed elements ÷Red Blood Cells(RBC) White Blood Cells (WBC) Platelets 6n8888g。 00 0D 0.0 o 00 0o。00o 0 SOo OQ 00 0 o0o8808 o800e8。 0 00 000080o°000
Formed elements Red Blood Cells (RBC) White Blood Cells (WBC) Platelets
Red blood cells (Erythrocytes) RBC count 6M:4.5-5.5×1012L 6F:3.8~4.6×1012L
Red blood cells (Erythrocytes) RBC count \M: 4.5~5.5 ×1012/L \F: 3.8~4.6 ×1012/L
Plasma Buffy Coat 人Whit lood Hematocrit:the volume of red blood cells as a percentage of centrifuged whole blood 6MI:45% 6F:42%
Hematocrit: the volume of red blood cells as a percentage of centrifuged whole blood \M: 45% \F: 42%
Functions 1.Transport of O2 and CO2 Plasma Alveolar air 02 eolar itial fiul
Functions 1. Transport of O2 and CO2