Mode of birth Delivery Affects Oral Microbiota in Infants 第五组赵钎虞逸静 郝雅婧邬开宬
第五组 赵钎 虞逸静 郝雅婧 邬开宬
Introduction
Introduction
Background 01 Four Background Facts
Background 01 Four Background Facts
Fact I 02 Differences of first exposure to micro rganism between vaginally delivered infants and c-section delivered ones 01 >Vaginally delivered: birth canal >C-section delivered: skin of parents and health providers, medical equipment
01 Fact I •Differences of first exposure to microorganism between vaginally delivered infants and C-section delivered ones. Vaginally delivered: birth canal; C-section delivered: skin of parents and health providers, medical equipment. 02
Fact ll 03 Modes of delivery lead to differences in the intestinal microbiota in infants Vaginally delivered: higher diversity 02 >C-section delivered: higher numbers of Clostridium difficile(艰难梭菌), delayed acquisition of bifidobacteria(双歧杆菌) and escherichia coli
02 Fact II • Modes of delivery lead to differences in the intestinal microbiota in infants. Vaginally delivered: higher diversity; C-section delivered: higher numbers of Clostridium difficile(艰难梭菌), delayed acquisition of bifidobacteria(双歧杆菌) and Escherichia coli. 03
FactⅢl 05 C-section compared with vaginal delivery, may be related with a reduced natural barrier 03 Mutans streptococci(变形链球菌)were detected more frequently and at a younger age in children delivered by c-section than in those delivered vaginally
Fact III • C-section, compared with vaginal delivery, may be related with a reduced natural barrier. Mutans streptococci(变形链球菌) were detected more frequently and at a younger age in children delivered by C-section than in those delivered vaginally. 03 05
Fact v 06 Lack of information about the establishment of the microbiota in oral cavit' y 04 >We know less information about factors influencing establishment of the microbiota in the oral cavity than reported for the gut
Fact IV 0 5 • Lack of information about the establishment of the microbiota in oral cavity. We know less information about factors influencing establishment of the microbiota in the oral cavity than reported for the gut. 043 06
THE AIM To compare oral microbiota and seeking differences in colonization patterns in infants delivered vaginally or by c section Vaginally delivered C-section
To compare oral microbiota and seeking differences in colonization patterns in infants delivered vaginally or by Csection. THE AIM Vaginally delivered C-section
Methods
Methods
Study Population 207 mothers v In northern Sweden C-section v Delivered a healthy baby selection in the previous 3 months Vaginally delivered √ Accpet the study 26 Mode of delivery ● body weight&| length Data ○ Antibiotics O Other possible confounders
Study Population Data Mode of delivery Antibiotics Body weight & length Other possible confounders 01 207 mothers In Northern Sweden Delivered a healthy baby in the previous 3 months Accpet the study selection C-section Vaginally delivered 41 26 11
