General embryology(I) Jun zhou(周俊) zhjjwm300@zju.edu.cn School of medicine, Zhejiang University 20190604
General embryology (I) Jun Zhou（周俊） zhjjwm300@zju.edu.cn School of Medicine, Zhejiang University 20190604
histology embryology Final score 1. Attendence (Lab, Lecture): 10% 2. Quiz: 15% 3 Lab test: 25%/ Final written exam: 50% Final written exam: Histology: 70-80%0 Embryology: 20-30% Item type .Single choice: 60, 1 point/per(60%) .Brief question: 5, 8 points/per (40%)
Final written exam: Histology: 70-80%, Embryology: 20-30% Item type： •Single choice: 60, 1 point/per (60%) •Brief question: 5, 8 points/per (40%) Histology & Embryology: Final score: 1. Attendence (Lab , Lecture): 10% 2. Quiz: 15% 3. Lab test: 25% 4. Final written exam.: 50%
Langmans Medical Embryology, 13 th Edition 2高英茂主编,《组织胚胎学》,全国八年制教材,人民卫生出版社, 2010 3课程网站:m- earning zju.edu.cn,2018组织胚胎学 Langman's Medical AMInaLVD Embryology 国真学秋 Thirteenth Edition 2低 组织学与胚胎学 histology and Embryology T W. Sadler 高英茂李 碱编李组采宋天强 人民里心队越 标准图片,品相见卖家述
1. Langman’s Medical Embryology，13 th Edition 2.高英茂主编，《组织胚胎学》，全国八年制教材，人民卫生出版社， 2010 3.课程网站：m-learning.zju.edu.cn, 2018组织胚胎学
OBJECTIVES ●1说明受精的过程和意义 2试述胚胎植入的定义过程、部位以 及植入后的子宫蜕膜分部。 3试述两胚层胚盘的形成过程和组成。 4.三胚层胚盘的形成和初步分化。 ●5胎膜、蜕膜及胎盘的结构与功能。 ●6先天性畸形
OBJECTIVES 1.说明受精的过程和意义。 2.试述胚胎植入的定义、过程、部位以 及植入后的子宫蜕膜分部。 3.试述两胚层胚盘的形成过程和组成。 4.三胚层胚盘的形成和初步分化。 5.胎膜、蜕膜及胎盘的结构与功能。 6.先天性畸形
Embryology a science which study the processes and regulations of development of human fetus. ( from 1 ce( (zygote合子)to(57)×10cel) total 40/38 weeks: 280 /266 days 未次月经 的第一天受精 受精龄,266天 分 月经龄,280天
▪ a science which study the processes and regulations of development of human fetus.(from 1 cell (zygote合子) to (5-7) x1012 cells) ▪ total 40/38 weeks: 280 /266 days 受精 分 娩 末次月经 的第一天 受精龄， 266天 月经龄， 280天 Embryology
● preembryonic period(胚前期): before2weks IL embryonic period(胚期):38 weeks 周 4周 周 8周 ● fetal period(胎儿期): after9 Weeks 9周16周 20-3638周
embryonic period（胚期）: 3-8 weeks fetal period（胎儿期）: after 9 weeks preembryonic period（胚前期）: before 2 weeks
Fertilization/(受精) Definition: the process by which the Ampulla site of fertilization (sperm cell penetrates oocyte) male and female gametes(sperm and Uterine tube ovum) unite to give rise to zygote ste: in the ampullary region(壶腹部) of the oviduct Oocyte Ovary Sperm cells deposited in vagina
Fertilization（受精） ▪ Definition: the process by which the male and female gametes (sperm and ovum) unite to give rise to zygote ▪site: in the ampullary region（壶腹部） of the oviduct
精相题O 卵细麗 初级精母 D(0X I 细胞46.XY 初级柳母细慰 D (届6,XⅩ Puting apart of 丹脱○ Anaphase of 1st 精子 细胞 22X23,Y23x123Y 次级卵母@极体 细胞23X V人 极体 ells resulted from 明f 23,X conditions: 1) maturation of oocyte 2)maturation of spermatozoa
conditions: 1) maturation of oocyte 2) maturation of spermatozoa
3) capacitation(获能) and acrosome reaction(顶体反应) ot spermatozoa capacitation factor: secreted by epi, cells of oviduct, /capacity of releasing acrosome enzymes 4)quality and quantity of spermatozoa 2-6ml,100,000,000/ml, 1.5 ml; or 30% or capacity for mobile< 70% 5)meeting of sperm and ovum within 24 hrs
3) capacitation （获能）and acrosome reaction（顶体反应） of spermatozoa • capacitation factor: secreted by epi. cells of oviduct, capacity of releasing acrosome enzymes 4) quality and quantity of spermatozoa: • 2-6 ml, 100,000,000/ml, • 30%; or capacity for mobile< 70% 5) meeting of sperm and ovum within 24 hrs
Processes of fertilization Corona radiata cells Phase i Phase1 Penetration of the corona radiata Polar body (放射冠), acrosomal release ● Phase ii Acrosom nner acrosomal Penetration of the zona pellucid(scm Secondary oocyte in 2nd meiotic 透明带) division ZP with receptors -zona pellucida Fusion oocyte and sperm cell membranes spongy- the release of local enzymes ● Phase iit Entrance, formation of zygote
Processes of fertilization: •Phase I –Penetration of the corona radiata （放射冠）, acrosomal release •Phase II –Penetration of the zona pellucide（ 透明带） –ZP with receptors – zona pellucida spongy – the release of local enzymes •Phase III –Entrance, formation of zygote