Vasculitides Fudan university Zhongshan Hospital Yuqiang
Vasculitides Fudan university Zhongshan Hospital Yuqiang
The term vasculitis refers to a heterogeneous group of disorders characterized pathologically by evidence of blood vessel inflammation and clinically by a diverse set of symptoms and signs
The term vasculitis refers to a heterogeneous group of disorders characterized pathologically by evidence of blood vessel inflammation and clinically by a diverse set of symptoms and signs
Pathol three types: 1 necrotize 2. granulomas 3. only inflammatory cellular infiltration in the vessel wall
Pathology three types： 1. necrotize 2. granulomas 3. only inflammatory cellular infiltration in the vessel wall
Cause to 1 vessel wall angusty, blunting、 fibrosis, aneurysm 2 tissue ischemia, functional impalement
Cause to 1.vessel wall angusty， blunting、 fibrosis， aneurysm 2. tissue ischemia， functional impaiement
CLASSIFCATIO小 1. histopathologic (1) necrotize (2) granulomas (3) leucocytoclasia (4) giant cell
CLASSIFICATION 1. histopathologic （1）necrotize （2）granulomas （3）leucocytoclasia （4）giant cell
2 clinical classific ● infectivity o un-InfectIvIty
2. clinical classific • infectivity • un-infectivity
3. clinical+ histopathologic primarily skin systemic secondary
3. clinical+ histopathologic primarily skin systemic secondary
Lie CLASSIFICATION primariy large-vessel Takayasu arteritis giant cell arteritis Medium-vessel polyarteritis nodosa Churg-Struss syndrom Wegener's granulomatosis small-vessel Microscopic polyangiitis Schonlein-Henoch syndrom
Lie CLASSIFICATION primarily large-vessel Takayasu artertis giant cell artertis Medium-vessel polyarteritis nodosa Churg-Struss syndrom Wegener’s granulomatosis small-vessel Microscopic polyangiitis Schonlein-Henoch syndrom
Secondary infective drug connective tissue disease associated with tumer
Secondary infectivity drug connective tissue disease associated with tumer
1 infectivity 2. immune complex 3. antineutrophil cytoplasmic antibody ANCA-PR3 ANCA-MPO 4. antibody attack vessel AECA GBM antibody 5ce‖ Immune 6. understand
pathogenesis 1. infectivity 2. immune complex 3. antineutrophil cytoplasmic antibody ANCA-PR3 ANCA-MPO 4.antibody attack vessel AECA GBM antibody 5.cell immune 6.understand