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复旦大学:《核技术概论 Introduction to nuclear technology》PPT课件_chapter 10 Medical Applications of Nuclear Technology

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Chanter 14 -- Medical Applications. of Nuclear Technology Xiaodong He Radiotherapy Center Shanghai Pulmonary Hospital

Chapter 14 -- Medical Applications of Nuclear Technology Xiaodong He Radiotherapy Center Shanghai Pulmonary Hospital

prologue Just after the moment of discovery of X rays the importance of X rays in medical diagnosis was immediately apparent, and within months of its discovery, the bactericidal action of X rays and their ability to destroy tumors were revealed

Just after the moment of discovery of X rays, the importance of X rays in medical diagnosis was immediately apparent , and within months of its discovery, the bactericidal action of X rays and their ability to destroy tumors were revealed. prologue

Today, both diagnostic and therapeutic medicine as well as medical research depend critically on many increasingly sophisticated applications of nuclear radiation and radioisotopes

Today, both diagnostic and therapeutic medicine as well as medical research depend critically on many increasingly sophisticated applications of nuclear radiation and radioisotopes

opticator 0 clear 010 Ni nuclear Radiation medicine Radiation O ncology Image 核医学 放射肿瘤 NMR 治疗学 Medical Applications of Nuclear Technology are constituted by three parts above

Nuclear medicine 核医学 Medical Applications of Nuclear Technology Radiation Oncology 放射肿瘤 治疗学 Radiation Image + NMR Medical Applications of Nuclear Technology are constituted by three parts above

Nuclear medicine O(Radioimmunoassay, RIA in vitro O y Camera, Bone Scanning O Single Photon Emission Computerized 体 Tomography SPECT O Positron Emission Tomography O PET/CT 内 ○ Radionuclide therapy Tumor, hyperthyroidism甲亢,etc O Radionuclide analysis in vitro t in vivo

Nuclear medicine Positron Emission Tomography Single Photon Emission Computerized Tomography SPECT γ Camera , Bone Scanning Radioimmunoassay,RIA in vitro 体 内 Radionuclide Therapy Tumor, hyperthyroidism甲亢, etc. PET/CT Radionuclide analysis in vitro + in vivo

Radionuclide analysis for human species According to the radioactive isotope analysis results of the Oak ridge(橡树岭)lab: In one year, 98% of the atoms of organism (human body) is replaced. The body does not have a constant material And in certain time the materials inside bod are to produce thousands of times biological chemical reactions every second

According to the radioactive isotope analysis results of the Oak Ridge(橡树岭) lab: In one year, 98% of the atoms of organism (human body) is replaced. The body does not have a constant material. And, in certain time the materials inside body are to produce thousands of times biological chemical reactions every second. Radionuclide analysis for human species

Radioimmunoassay ( more compactly as RIA放射免疫技术) RIA as a kind of technology take the both advantages of accuracy and sensitivity of the radioactive isotope measurement and the specificity of the reaction of antigen and antibody It is a new in vitro technology for ultra trace (10 9x10-5g) material detection 放射免疫技术为一种将放射性同位测量的高度灵敏性 精确性和抗原抗体反应的特异性相结合的体外测定超微量 (1039~1015g)物质的新技术

Radioimmunoassay (more compactly as RIA 放射免疫技术) RIA as a kind of technology take the both advantages of accuracy and sensitivity of the radioactive isotope measurement and the specificity of the reaction of antigen and antibody. It is a new in vitro technology for ultra trace (10- 9~10-15g) material detection. 放射免疫技术为一种将放射性同位素测量的高度灵敏性、 精确性和抗原抗体反应的特异性相结合的体外测定超微量 (10-9~10-15g)物质的新技术

Broadly, all the assay technologies via immune reactions by antigen and antibody which tagged by radioactive isotopes can be called RIA 广义来说,凡是应用放射性同位素标记的抗原或抗体,通 过免疫反应测定的技术,都可称为放射免疫技术。 So far has development to the fifth generation of RIA technology. It is characterised by the combination of magnetic particles and ria or IRMA (immunoradiometric assay

Broadly, all the assay technologies via immune reactions by antigen and antibody which tagged by radioactive isotopes can be called RIA 广义来说,凡是应用放射性同位素标记的抗原或抗体,通 过免疫反应测定的技术,都可称为放射免疫技术。 So far has development to the fifth generation of RIA technology. It is characterised by the combination of magnetic particles and RIA or IRMA (immunoradiometric assay)

PET/ CT PoSitron emission tomography CT PET/CT is a perfect fusing of PET and ct. It can Provide detailed lesion function and metabolic information of moleculars by PEt, and in the same time, provide the accurate lesion anatomic localization by CT It is characterised by sensitivity, accuration specific and accurate location It is extensive used in radiotherapy, and also be called the high-tech coronal of Modern medicine

PET / CT Positron emission tomography + CT PET/CT is a perfect fusing of PET and CT. It can Provide detailed lesion function and metabolic information of moleculars by PET , and in the same time, provide the accurate lesion anatomic localization by CT. It is characterised by sensitivity, accuration, specific and accurate location. It is extensive used in radiotherapy, and also be called the “high-tech coronal of Modern medicine

The mechanics of PEt The clinical imaging process of PET is as followed ark the radioactive isotopes which can emit positrons(such as F-18)to compounds which be gonna to participate in tissue blood flow, or in metabolic process. b. Inject the tagged compounds into human body

The Mechanics of PET The clinical imaging process of PET is as followes: a. Mark the radioactive isotopes which can emit positrons (such as F-18) to compounds which be gonna to participate in tissue blood flow, or in metabolic process. b. Inject the tagged compounds into human body

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