损伤的修复Repair of the injury
Repair of the injury 损伤的修复
tissue and cellular injuryNormal cellsirreversibleAdaptationinjuryreversibleinjuryAdaptation hypertrophy hyperplasiaatrophy metaplasiareversible :cellular injuryNecrosisirreversible: apoptosis
Logo tissue and cellular injury cellular injury reversible : irreversible : Necrosis apoptosis Adaptation hypertrophy hyperplasia atrophy metaplasia Normal cells irreversible injury reversible injury Adaptation
损伤的修复Repairoftheinjury损伤(injury)一→>缺损(defect)一修复(repair)LUSU
损伤 Logo (injury)→缺损(defect)修复(repair) 损伤的修复 Repair of the injury
Repair of the injuryRepairis theprocess bywhich necrotic cells arereplacedby viable (living)cells (regeneration)orby scar formation. The structure and function ofthetissuecanberecoveredbyrepair.修复（repair）：损伤造成机体部分细胞和组织丧失后，机体对所形成缺损进行修补恢复的过程，修复后可完全或部分恢复原组织的结构和功能。再生纤维性修复RegenerationRepairbyScarformation由损伤周围的由纤维结缔组织来修复同种细胞来修复瘢痕修复-Logo
Logo 修复(repair)：损伤造成机体部分细胞和组织丧失后，机 体对所形成缺损进行修补恢复的过程，修复后可完全或部 分恢复原组织的结构和功能。 Repair is the process by which necrotic cells are replaced by viable (living) cells (regeneration) or by scar formation. The structure and function of the tissue can be recovered by repair. Repair of the injury 再生 Regeneration 纤维性修复 Repair by Scar formation 由损伤周围的 同种细胞来修复 由纤维结缔组织来修复 -瘢痕修复 再生 Regeneration
Repairof the injury再生（Regeneration）：由损伤周围的同种细胞来修复Aprocessthatthe necroticparenchymal cellswerereplacedbynewparenchymal cellsofthesametypeThe new cells complement aging cells.physiologicMaintain the normal structure and functionThe regeneration occurs after cellular andpathologictissue defect.Logo
Logo 再生(Regeneration)：由损伤周围的同种细胞来修复 A process that the necrotic parenchymal cells were replaced by new parenchymal cells of the same type The new cells complement aging cells. Maintain the normal structure and function The regeneration occurs after cellular and tissue defect. Repair of the injury physiologic pathologic
Repair of the injury --regenerationCell types---Base on regenerative capacityCell cycle-is defined as the periodbetweentwo successivecell divisions.It is dividedinto 4 unequal phases.sLabile cellsContinuouslycyclinglabilecells(e.g.,epidermis)DNAsynthesisSStablecellsG1G2PermanentcellsMMitosisGoQuiescent(e.g.,cardiacmyocyte)stablecells(e.g.,hepatocytes)(e.g.,neuron)Nondividingpermanentcells
Logo ⚫ Labile cells ⚫ Stable cells ⚫ Permanent cells Cell types-Base on regenerative capacity Repair of the injury -regeneration Cell cycle—is defined as the period between two successive cell divisions. It is divided into 4 unequal phases
Repairofthe injury再生(Regeneration)The regenerative capacity types of cells-1不稳定细胞LabilecellsThey are continuously dividing cells. They multiplythroughout life under normal physiologic conditionsThe chances of restoration by regeneration areexcellent.Including:surface epithelialcellsof epidermis,digestive, respiratory,and urinary tracts, uterineendometrium,haematopoieticcellsof bone marrowand cells of lymph nodes and spleenLogo
Logo The regenerative capacity types of cells-1 1 不稳定细胞 Labile cells ⚫ They are continuously dividing cells. They multiply throughout life under normal physiologic conditions ⚫ The chances of restoration by regeneration are excellent. ⚫ Including: surface epithelial cells of epidermis, digestive, respiratory, and urinary tracts, uterine endometrium, haematopoietic cells of bone marrow and cells of lymph nodes and spleen 再生(Regeneration) Repair of the injury
Repairof the injury再生（Regeneration)The regenerative capacity types of cells-2稳定细胞Stablecells（quiescentcells）They are in the resting phase (Go)but can bestimulated to enter the cell cycle. They retain thecapacity to multiply in response to stimuli.Chances of regenerationremainIncluding:parenchymal cells of organs like liver,andthyroid;kidneys,adrenalpancreas，cellsandlike,fibroblastsmesenchymalendothelium.Logo
Logo ⚫ They are in the resting phase (G0 ) but can be stimulated to enter the cell cycle. They retain the capacity to multiply in response to stimuli. ⚫ Chances of regeneration remain ⚫ Including: parenchymal cells of organs like liver, pancreas ， kidneys, adrenal and thyroid; mesenchymal cells like, fibroblasts and endothelium. The regenerative capacity types of cells-2 Repair of the injury 2 稳定细胞 Stable cells (quiescent cells) 再生(Regeneration)
Repair of the injury再生（Regeneration）The regenerative capacity types of cells-33永久性细胞PermanentcellsThey are non-dividing cells whichhave left thecell cycle and die after injury.Including:: neurons, skeletal muscle and cardiacmuscle cellsThe peripheral nerve has retained the capacity forregeneration withdamageLogo
Logo ⚫ They are non-dividing cells which have left the cell cycle and die after injury. ⚫ Including: neurons, skeletal muscle and cardiac muscle cells ⚫ The peripheral nerve has retained the capacity for regeneration with damage. The regenerative capacity types of cells-3 Repair of the injury 3 永久性细胞 Permanent cells 再生(Regeneration)
组织的再生过程Regenerativeprocess of tissues刘翔受伤位置（跟腱）utns疯狂运动会五米跳板阿能发生经微新制HINALogo
Logo 组织的再生过程 Regenerative process of tissues