AVM: a TLA for the Cns CEREBRAL ARTERIOVENOUS MALFORMATIONS
CEREBRAL ARTERIOVENOUS MALFORMATIONS AVM: a TLA for the CNS
Incidence 0. 52% at autopsy Slight male preponderance(1.09 to 1.94) Congenital lesions(although rarely familial
Incidence 0.52% at autopsy Slight male preponderance (1.09 to 1.94) Congenital lesions (although rarely familial)
Embryology First half of third week of gestation epiblastic cells migrate to form mesoderm mesodermal cells differentiate to arterial and venous vessels on the sur face of the embryonic nervous system
Embryology First half of third week of gestation epiblastic cells migrate to form mesoderm mesodermal cells differentiate to arterial and venous vessels on the surface of the embryonic nervous system
Embryology First half of third week of gestation epiblastic cells migrate to form mesoderm mesodermal cells differentaite to arterial and venous vessel on the surface of the embryonic nervous system Seventh gestational week vessels sprout branches penetrate developing brain reach the gray-white interface, either loop back to pial surface or traverse entire neural tube, thus epicerebral transcerebral circn eventually connect arterial and venous systems by around the twelfth week
Embryology First half of third week of gestation epiblastic cells migrate to form mesoderm mesodermal cells differentaite to arterial and venous vessels on the surface of the embryonic nervous system Seventh gestational week vessels sprout branches & penetrate developing brain reach the gray-white interface, either loop back to pial surface or traverse entire neural tube, thus epicerebral & transcerebral circ'n eventually connect arterial and venous systems by around the twelfth week
Pathology pathophysiology absence of normal capillary system
Pathology & Pathophysiology absence of normal capillary system
Pathology pathophysiology absence of normal capillary system usual function displaced
Pathology & Pathophysiology absence of normal capillary system usual function displaced
Pathology pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth
Pathology & Pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth
Pathology pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth vessels change with time may develop aneurysms
Pathology & Pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth vessels change with time may develop aneurysms
Pathology pathophysiology absence of normal parenchymal changes capillary system within and around the usual function displaced lesion asymptomatic at birth vessels change with time may develop aneurysms
parenchymal changes within and around the lesion Pathology & Pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth vessels change with time may develop aneurysms
Pathology pathophysiology absence of normal parenchymal changes capillary system within and around the usual function displaced lesion asymptomatic at birth site frequency is vessels change with proportional to brain time volume may develop aneurysms
parenchymal changes within and around the lesion site frequency is proportional to brain volume Pathology & Pathophysiology absence of normal capillary system usual function displaced asymptomatic at birth vessels change with time may develop aneurysms
